Job Postings

To post a job on our site, please email metroflowsc@gmail.com

Attach the posting as a Word document and be sure to include instructions on how a candidate should apply.

There is no fee for posting, as this is a complimentary service that we provide to the Cytometry community.

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Posted April 14,2021

Quality Control Scientist Cell Therapy Flow Cytometry

Bristol Myers Squibb

Summit West - NJ - US

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

 

Purpose and Scope of Position

 

This is a Sunday - Wednesday AM shift (8:00am-6:00pm).

 

The QC Scientist is responsible for supporting Quality Control bioanalytical testing for the release of clinical and commercial products.  This includes the ability to interface with multiple groups, the ability to independently perform tasks, interpret results, and troubleshoot.  Additionally, when needed, this position will be able to assist with training and assay transfer. 

 

Required Competencies: Knowledge, Skills, and Abilities

  • Advanced hands-on experience with various analytical techniques primarily flow cytometry, PCR, ELISA, Western Blot, and scientific knowledge in the characterization and transfer of pharmaceutical products.

  • Advanced ability to accurately and completely understand, follow, interpret and apply Global Regulatory and cGMP requirements.

  • Advanced technical writing skills.

  • Advanced problem-solving ability/mentality, technically adept and logical.

  • Ability to represent the interests of the group on cross-functional teams.

  • Ability to work independently in a high-paced team environment, meet deadlines, and prioritize work from multiple projects.

  • Ability to work with management locally and globally.

  • Advanced ability to communicate effectively with peers, department management and cross-functional peers.

 

Duties and Responsibilities

 

Perform testing of the in-process, final product, and stability samples

  • Utilize scientific principles to assist in analytical testing methods and the proper use of laboratory equipment.

  • Capable of handling complex issues and solving problems with only general guidance.

  • Prepare and present continuous improvement projects to management.

  • Comprehensive understanding of regulatory guidelines and can independently develop, write and execute methods, protocols, reports and other related documents.

  • Complete all work in a timely manner.

 

Perform peer review of testing data.

  •  Review all data in accordance with applicable procedures and cGMP requirements.

  •  Apply technical knowledge and abilities to ensure all testing is performed in a compliant manner.

  • Complete all reviews in accordance with required release timelines.

  • Communicate effectively with peers, and demonstrate teamwork, with regards to results of review and corrections required.

 

Train new analysts to general job duties.

  • Complete necessary training to become a qualified trainer.

  • Perform training effectively.

  • Document training per procedural and cGMP requirements.

 

Support document revision, project, CAPA, and investigation/deviation tasks.

  • Perform assigned tasks within a CAPA, deviation, or project

  • Participate in complex projects and continuous improvement efforts.

  • Draft and review technical documents, such as SOPs and protocols/reports.

  • Communicate effectively with management regarding task completion, roadblocks, and needs.

  • Demonstrate initiative, courage, and continuous improvement throughout investigation/corrective action lifecycles.

 

Education and Experience

  • Bachelor’s degree required, preferably in Science.

  • Advanced Degree preferred.

  • 5+ years of relevant analytical testing or QC experience or equivalent combination of education and experience, preferably in a regulated environment.

  • Demonstrated experience working with polychromatic flow cytometry panels and flow cytometry data analysis.

 

Working Conditions

  • The incumbent should be able to distinguish colors and possess correctable vision to 20/20, annual eye exam is required.

  • The incumbent must analyze numerical values on a daily basis.

  • The incumbent will be working a laboratory setting up to six (6) hours per day.

  • The incumbent will be working around biohazardous materials, including chemical agents up to six (6) hours per day.

 

This job description is intended to describe the general nature and level of work being performed by the person assigned to this position. The primary duties and responsibilities are intended to describe those functions that are essential to the performance of this job.

 

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. There are other duties and responsibilities that are considered incidental or secondary to the overall purpose of this job. Employees holding this position will be required to perform any other job-related duties as requested by management.

 

BMSCART

 

 

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

 

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. 


Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Apply

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Posted April 14,2021

Sr Supervisor QC Flow Cytometry

Bristol Myers Squibb

Summit West - NJ - US

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

 

 

This is a Wed-Sat AM shift

 

Purpose and Scope of Position:

The Sr Supervisor, QC Flow Cytometry is responsible for all operational aspects of the QC Flow Cytometry department at the CAR T manufacturing facility during clinical and commercial phases. This department is responsible for Flow Cytometry based testing of in-process samples, final drug product testing, stability testing, Validation and requalification support, critical reagent testing and qualification, training and other critical support as needed. The Sr. Supervisor, QC Flow is responsible for continuously maintaining the GMP status of the QC Laboratory, applying and ensuring staff complies to EHS rules and safe work practices per applicable procedures, while still hand-on testing as needed. This is a Wed-Sat shift.

 

Required Competencies: Knowledge, Skills, and Abilities

  • Extensive experience with flow cytometry and cell imaging, including flow related technologies related to analysis

  • Advanced knowledge of cGMP, ISO, FDA, MHRA, PMDA, USP, PDA, JP, and EP regulations and guidelines as related to the manufacture of cell therapy products.

  • Advanced verbal and written communication skills with the ability to tailor style for a wide variety of audiences 

  • Ability to collaborate cross functionally to drive operational and quality excellence.

  • Advanced organizational and time management skills.

  • Demonstrated critical reasoning, problem solving, troubleshooting, investigation, and decision-making skills.

  • Advanced teamwork and facilitation skills.

  • Advanced mentoring and coaching, influencing, negotiating, and personal interaction skills.

  • Requires strategic thinking and ability to work independently.

  • Demonstrated leadership and management skills, including establishing strategic direction and goals, and guiding execution while fostering a team-based environment.

  • Advanced knowledge of Quality Systems including SOPs, Change Controls, Deviations, CAPAs, and Risk Assessments.

  • Ability to interpret and author general, technical, and complex business documents.

  • Advanced knowledge and implementation of data integrity principles.

  • Ability to represent the department in regulatory inspections.

  • Requires strong qualitative training skills: responsiveness, enthusiasm, humor, sincerity, honesty, flexibility, and tolerance.

  • Proficiency in MS Office applications.

 

Duties and Responsibilities:

Manages all activities related to the QC Flow department including:

  • GMP release of in-process and drug product testing results.

  • Documentation of GMP release activities.

  • Method development and validation.

  • Oversight and qualification of contract testing laboratories.

 

Manages and develops direct reports including:

  • Management and scheduling of personnel within the department to meet manufacturing and laboratory schedules and needs.

  • Ensuring employees are properly trained and qualified to perform their assigned tasks, providing performance evaluations, and supporting career development of direct reports.

  • Performs other tasks as assigned.

 

Education and Experience

  • Bachelors’ degree required, preferably in Chemistry, Microbiology, or related science.

  • Advanced degree preferred.

  • 3-5 years of relevant work experience required.

  • 1-3 years of people management preferred.

 

Working Conditions:

  • The incumbent will be required to work in office and laboratory environments.

·      The incumbent may be required to gown for entry into the Aseptic Core and other supporting areas on an as-needed basis.

·      The incumbent (or designee) will be expected to be on call to support manufacturing issues involving sampling and/or test excursions or questions during shift operations.

·      Occasional travel may be required.

 

This job description is intended to describe the general nature and level of work being performed by the person assigned to this position.  The primary duties and responsibilities are intended to describe those functions that are essential to the performance of this job.

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position.  There are other duties and responsibilities that are considered incidental or secondary to the overall purpose of this job.  Employees holding this position will be required to perform any other job-related duties as requested by management.

 

 

BMSCART

 

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

 

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. 


Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Apply

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Posted March 22,2021

Flow Cytometrist

The Flow Cytometry Core Facility at EMBL

Heidelberg, Germany

Staff Category: Staff Member
Contract Duration: 3 years (renewable)
Grading: 4, 5 or 6; depending on qualifications and experience
Closing Date: 09/04/2021
Reference Number: HD01944

The Flow Cytometry Core Facility at EMBL is looking for an enthusiastic master or Ph.D. holder with a strong background in Flow Cytometry and Data Analysis. As a core facility, we provided key services to multiple research groups at EMBL Heidelberg and external users from our member-states. The facility supports scientific projects ranging from cell biology, stem cell biology, advanced genome biology, immunology, microbiology and developmental biology. The facility is equipped with high-end cell sorters and analyzers from BD Biosciences, Beckman Coulter, and Cytek and provides access to single-cell sequencing technology in cooperation with EMBL's Genomics core facility.

Your role

As our successful candidate, you will join a small, international team with a primary focus on hands-on user support on: experimental design, flow cytometry analysis, cell sorting and data analysis. The secondary focus will be to support the team in the daily instrument set-up and maintenance.

Your responsibilities include, but are not limited to:

  • Provide scientific and technical expertise for the design and execution of flow cytometry experiments

  • Support users at the facility when performing analyses and cell sorting

  • Support users with their data analysis questions

  • Participate in training activities within the internal and external EMBL training programme

  • Prepare protocols and standard operating procedures (SOPs) for routine applications

  • Perform all necessary daily maintenance routines

  • Organize and manage the general laboratory, including timely purchases and stocking of supplies

 

You have

A good background in flow cytometry and data analysis with a minimum of 3 years of hands-on experience is a prerequisite for this position. The operation of cell sorters and the maintenance of flow cytometry equipment can be learned at the facility.

Minimum requirements:

  • Education: Master or Ph.D. in Immunology, Developmental Biology, Molecular Biology or related subject area

  • Relevant experience including hands-on, in-depth experience in flow cytometry and cell-based assays

  • Excellent knowledge of English – oral and written

  • Good knowledge of data analysis using either FlowJo or FCSExpress at a level that allows for user support and training

  • Good knowledge of either DiVa, Summit, or FACSChorus at a level that allows training of new users

  • Demonstrated ability to work collaboratively in a fast-paced team environment and quickly acquire new technical skills and knowledge

  • Demonstrated ability to interact with researchers holding diverse scientific backgrounds

  • Very good communication skills along with strong service oriented attitude

 

You might also have

  • Hands-on experience with cell sorting and single-cell technologies

  • Advanced experience in multi-parametric data analysis, including: dimensionality reduction and automatic clustering tools

 

Why join us

The position provides a great chance to grow deep technical knowledge and learn how core facilities offer outstanding scientists the best possible service. EMBL's core facilities are actively cooperating on a level that allows learning skills across platforms. Our team is small and extremely supportive and thrives on collegial appreciation.

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organization with a very collegial and family-friendly working environment. The remuneration package comprises a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including your family and the availability of an excellent child care facility on campus.

What else you need to know

We are Europe's flagship research laboratory for the life sciences -an intergovernmental organization performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1700 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research.


Please apply online through: www.embl.org/jobs
 

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Posted February 25,2021

Technical Applications Specialist

De Novo Software

Location, see below

De Novo Software is looking for a motivated individual to join our team as a Technical Applications Specialist.

Our company is growing rapidly and offers a dynamic work environment and cutting-edge technology.  The successful candidate will be located close to an area with a high concentration of flow cytometry activity (labs, companies etc).

Job Duties:

  • Technical support via phone, email and remote access

  • One-on-one Training

  • Writing technical documentation, tutorials, manuals, and web site content

  • Representing De Novo Software at trade shows

  • Scheduling presentations and demonstrating software at Flow Cytometry Core labs in universities and companies

  • Obtaining customer feedback

  • Suggesting new features and improvements to software

  • The position will involve approximately 50% travel (predominately in the USA but also worldwide).

Required Experience:

  • 5 years experience in analyzing flow cytometry data, preferably with many different data analysis software packages

  • Extensive general computer experience with common MS Windows applications (Word, Excel, PowerPoint, etc.)

  • Excellent English, interpersonal, presentation, communication, and software skills.

  • Must have valid passport and drivers license

  • Able to provide pre and post installation application support.

  • Able to interact with sales, sales support, customers, scientists.

  • Self-motivated, high energy, deadline and goal-oriented individual.

Preferred Experience:

  • Previous technical application specialist or sales experience

  • Use of specialized flow cytometry techniques: cell cycle, proliferation, calcium flux analysis

  • Use of a non-flow cytometry data analysis tools

  • Experience with imaging cytometry (Amnis, Cellomics, etc.)

  • Masters or PhD

  • Background in imaging applications.

 

Salary is commensurate with experience.

Please send your resume, or any questions, to jobs@denovosoftware.com.

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Posted February 23,2021

Quality Control Associate III

Bristol Myers Squibb

Bothell, Washington / Summit, New Jersey

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

 

We have multiple openings within Flow Cytometry. This is a sample of one of our openings. Please send resumes to aaron.rinehart@bms.com.

 

This is a Wed- Sat PM Shift - 1:30p - midnight

 

PURPOSE AND SCOPE OF POSITION:

The primary focus of the Quality Control Associate III role will be to support product lot release and in-process testing within a cGMP environment. Additionally, this role will provide technical support and troubleshooting for the support of lot release, in-process, and stability testing.

 

REQUIRED COMPETENCIES:  Knowledge, Skills, and Abilities:

Education:

  • BS in a scientific discipline.

 

Experience

  • 6+ years of analytical QC testing within a regulated environment, or equivalent combination of education and experience.

  • Experience working in a regulated (GxP) environment and familiarity with flow cytometry preferred.

  • Demonstrated success working in a high-performing, business results-driven environment.

 

Knowledge, Skills, and Abilities

  • Ability to work in a high paced team environment, meet deadlines, and prioritize work from multiple projects without supervision.

  • Strong analytical and communication skills.

  • Computer proficiency as well as strong scientific and organizational skills.

  • Experience working in a GMP environment.

  • Demonstrated success working in a high-performing, business results-driven environment.

  • Strong analytical and communication skills as well as sound judgment, with the ability to work effectively with others.

  • Ability to maintain flexible intellect and adjust to a dynamic work environment.

  • Detail-oriented with strong time-management skills.

 

DUTIES AND RESPONSIBILITIES:

Key Responsibilities

  • Perform or support cGMP lot release, in-process, and stability testing using flow cytometry.

  • Ensure timely completion of testing and tasks as assigned.

  • Perform assay and form review.

  • Lead assay transfer and method validation of by representing site QC in cross-site validation protocols and providing data to support final reports.

  • Participate in cross-functional training.

  • Author and revise test methods, SOPs, raw material specification, and/or sample plans as appropriate.

  • Identify and facilitate continuous improvements.

  • Execute technical transfer and validation protocols for QC assays.

  • Maintain instrumentation and equipment preventative maintenance and supporting documentation in a cGMP compliant manner.

  • Assist in the implementation of new assay methodologies and the associated instrumentation.

  • Identify and support initiation and completion of Deviations, CAPAs and Laboratory Investigations.

  • Act as a lead in small to medium scale projects.

  • Act as owners for Deviation, CAPA, Laboratory Investigations, and Change Controls records.

  • Train other on QC processes and procedures

 

This job description is intended to describe the general nature and level of work being performed by the person assigned to this position. The primary duties and responsibilities are intended to describe those functions that are essential to the performance of this job.

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. There are other duties and responsibilities that are considered incidental or secondary to the overall purpose of this job. Employees holding this position will be required to perform any other job-related duties as requested by management.

 

WORKING CONDITIONS (US Only):

  • While performing the duties of this job, the employee is frequently required to stand; walk; sit; bend; stretch; use hands and fingers, with various manipulations; reach with hands and arms; and effectively communicate with others in the workplace, including the ability to make and promptly respond to audible cues and warnings.

  • Work in areas that may have strong magnets.

  • May work in areas with exposure to vapor phase liquid nitrogen.

  • Must have ability to work assigned shift (Day, Night, Weekends and/or holidays).

  • Will be required to wear personal protective equipment (PPE) and other clean room garments daily. This may include, but not limited to: safety shoes, safety glasses, aprons, face shields, lab coats, full body gowns, hairnets, gloves, and hearing protection.

  • Require to work in and around laboratories and controlled, enclosed, restricted areas, included clean rooms.

  • Require to carry and/or lift up to 10 pounds several times a day.

 

Please send resumes to: aaron.rinehart@bms.com

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

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Posted February 10,2021

Technical Assistant II, Core (Flow Cytometry Core Facility)

Whitehead Institute for Biomedical Research

Cambridge, Massachusetts

Position Summary:

Whitehead Institute for Biomedical Research is a leading, nonprofit research and educational institution that  has defined the cutting edge of biomedical science, creating a legacy of research excellence and academic  eminence since 1982. Wholly independent in its governance, finances and research programs, Whitehead  shares a teaching affiliation with Massachusetts Institute of Technology (MIT), offering the intellectual,  collegial and scientific benefits of a leading research university. Whitehead’s Faculty Members and Fellows  run pioneering programs in cancer research, immunology, developmental biology, stem cell research,  regenerative medicine, genetics and genomics—programs with a record of success. 

We offer excellent benefits including a choice of health insurance options; a generous retirement  plan; comprehensive dental, disability and life insurance coverage; competitive salary, substantial  vacation and holiday time; and programs for tuition reimbursement, dependent care assistance, pre tax spending accounts, and subsidized public transportation or parking.  

Whitehead Institute is an Equal Opportunity Employer. 

Classification: Exempt; Administrative Staff 

Reports To: Flow Cytometry Core Facility Manager 

Overall Responsibility 

We are seeking a Technical Assistant II, Core (Flow Cytometry Core Facility) to join our team! 

The primary duty of the FACS Technician II of the BSL2 core cytometry facility is to  provide high quality flow cytometry service and support to the Whitehead Institute investigators and Boston  research community. The FACS Technician will possess high level of proficiency on the BD FACSAria  SORP in order to perform quality high-speed cell sorting. Additional duties include but are not limited to  development of proficiency on core facility benchtop analyzers: the BD LSRII SORP, BD LSRFortessa with  HTS, and BD FACSCanto with HTS and the SONY cell sorter. Other duties will be performed as scheduled  or needed. All duties will be performed in accordance with the Whitehead Institute’s behavioral standards,  safety standards, and mission. 

 

Characteristic Duties 

Cytometry Instrumentation and associated Software and Peripherals 

High Speed Cell Sorter- BD FACSAria SORP and SONY cell sorter 

• Perform high quality, High Speed Cell Sorting for researchers 

• Perform scheduled and unscheduled maintenance, including data backup as maintenance  • Perform daily quality control and monitor instrument performance 

• Troubleshoot sorter and associated software and peripherals 

• Contact and interact with vendor service and FACSAria/ SONY field service engineers as needed • Log sorter and related software and peripheral problems and report to core staff • Enter Aria/ SONY usage into database  

Benchtop Analyzers- BD LSR II SORP, BD FACSLSRFortessa HTS, BD FACSCanto HTS 

• Develop and maintain proficiency with all benchtop analyzers and associated software and peripherals • Perform scheduled and unscheduled maintenance, including data backup 

• Perform quality control and monitor instrument performance 

• Troubleshoot benchtop analyzers and associated software and peripherals 

• Contact and interact with vendor service and FACS benchtop analyzer field service engineers as  needed 

• Log benchtop analyzer and related software and peripheral problems and report to core staff

 

Service 

• Provide high quality service to researchers 

• Work closely with researchers and Whitehead Institute staff to maintain good relationships • Orient new users to the lab 

• Assist researchers with their scheduling needs 

• Advise researchers on basic requirements for high speed cell sorting and benchtop Cytometer usage • Address problems immediately, if possible, log, and report to manager 

 

Administrative 

• Maintain sort appointment waiting list and notify researchers if an appointment is available • Log lateness and failure to cancel appointments 

• Approve sort appointments in Calendar system 

• Notify researchers of unscheduled instrument downtime 

• Assist with writing protocols and other writing as needed 

• Assist with ordering of supplies and billing as needed 

 

Operations 

• Prepare reagents as needed 

• Autoclave as needed 

• Assist with inventory and stocking of laboratory supplies 

• Maintain all work areas 

 

Other 

• Attend a minimum of one flow cytometry workshop, seminar, vendor show, or core lab visit per year • Attend a Whitehead Institute retreat 

• Become familiar with flow cytometry journals, associations, and resources 

• Assist with demos and tours as needed 

• Audit training sessions and provide feedback 

 

Qualifications 

• B.S. degree in biological or physical sciences or related discipline; MS degree and PhD are welcomed • Must have 3 - 5 years of experience on the BD FACSAria

 

SORP 

• Excellent organizational, problem-solving, and communication skills 

• Must be available to work flexible hours 

• Must be able to work well with minimal supervision and with researchers, engineers, and institute staff in a service-oriented environment 

 

Interested candidates should submit a resume to resumes@wi.mit.edu

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Posted February 10,2021

Technical Assistant I, Core (Flow Cytometry Core Facility)

Whitehead Institute for Biomedical Research

Cambridge, Massachusetts

Position Summary:

Whitehead Institute for Biomedical Research is a leading, nonprofit research and educational  institution that has defined the cutting edge of biomedical science, creating a legacy of research  excellence and academic eminence since 1982. Wholly independent in its governance, finances  and research programs, Whitehead shares a teaching affiliation with Massachusetts Institute of  Technology (MIT), offering the intellectual, collegial and scientific benefits of a leading research  university. Whitehead's Faculty Members and Fellows run pioneering programs in cell biology, cancer research, immunology, developmental biology, stem cell research, regenerative medicine,  genetics and genomics--programs with a record of success. 

  

We offer excellent benefits including a choice of health insurance options; a generous retirement  plan; comprehensive dental, disability and life insurance coverage; competitive salary, substantial  vacation and holiday time; and programs for tuition reimbursement, dependent care assistance,  pre-tax spending accounts, and subsidized public transportation or parking.  

Whitehead Institute is an Equal Opportunity Employer.  

  

Classification: Exempt; Administrative Staff 

Reports To: Flow Cytometry Core Facility Manager 

  

OVERALL RESPONSIBILITY  

The primary duty of the FACS Technician of the BSL2 core cytometry facility is to provide high  quality flow cytometry service and support to the Whitehead Institute investigators and Boston  research community. The FACS Technician will develop and maintain a high level of proficiency  on the BD FACSAria SORPs and the SONY SH800 in order to perform quality high speed cell  sorting. Additional duties include but are not limited to development of proficiency on core facility  benchtop cytometers: the BD LSRII SORP, BD LSRFortessa SORP with HTS, and BD  FACSCanto with HTS. Other duties will be performed as scheduled or needed. All duties will be  performed in accordance with the Whitehead Institute’s behavioral standards, safety standards,  and mission. 

  

CHARACTERISTIC DUTIES 

High Speed Cell Sorters- BD FACSAria SORPs and SONY SH800  

• Perform high quality, High Speed Cell Sorting for researchers 

• Perform scheduled and unscheduled maintenance, including data backup as  maintenance  

• Perform daily quality control and monitor instrument performance 

• Troubleshoot sorter and associated software and peripherals 

• Contact and interact with vendor service and FACSAria and SONY SH800 field service  engineers as needed 

• Log sorter and related software and peripheral problems and report to core staff • Enter Aria and SONY SH800 usage into database  

  

  

Benchtop Cytometers- BD LSR II SORP, BD FACSCanto-HTS, BD LSRFortessa-HTS  

• Develop and maintain proficiency with all benchtop cytometers and associated software  and peripherals 

• Perform scheduled and unscheduled maintenance, including data backup

• Perform quality control and monitor instrument performance 

• Troubleshoot benchtop cytometers and associated software and peripherals. • Contact and interact with vendor service and FACS benchtop cytometer field service  engineers as needed 

• Log benchtop cytometer and related software and peripheral problems and report to core  staff 

  

Service  

• Provide high quality service to researchers 

• Work closely with researchers and Whitehead Institute staff to maintain good  relationships 

• Orient new users to the lab 

• Assist researchers with their scheduling needs 

• Advise researchers on basic requirements for high-speed cell sorting and acquisition of  data on benchtop cytometers 

  

Administrative  

• Maintain sort appointment waiting list 

• Log lateness and failure to cancel appointments 

• Approve sort appointments in Calendar system 

• Notify researchers of unscheduled instrument downtime 

• Assist with writing protocols and other writing as needed 

• Assist with ordering of supplies and billing as needed 

  

Operations  

• Prepare reagents as needed  

• Autoclave as needed  

• Assist with inventory and stocking of laboratory supplies  

• Maintain all work areas  

Other  

• Attend a minimum of one flow cytometry workshop, seminar, vendor show, or core lab  visit per year 

• Attend a Whitehead Institute retreat 

• Become familiar with flow cytometry journals, associations, and resources • Assist with demos and tours as needed 

• Audit training sessions and provide feedback 

  

QUALIFICATIONS  

  

• B.S. degree in biological or physical sciences required 

• 1+ years of flow cytometry experience. 

• Ability to work Monday – Friday, 8a – 430p. 

• Must be able to work well with minimal supervision and with researchers, engineers, and  institute staff in a service- oriented environment 

• Excellent problem-solving skills 

• Strong organizational and communication skills 

Interested candidates should submit a resume to resumes@wi.mit.edu

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Posted February 10,2021

Scientist III/IV, Biotherapeutics (Antibody Generation)

Boehringer Ingelheim

Ridgefield, CT

Position Summary:

Candidate will be hired at level commensurate with experience and education

 

Description:

Boehringer Ingelheim is currently seeking a talented and innovative Scientist III/IV to join the Antibody Generation Group within the Biotherapeutics Department located at our US headquarters in Ridgefield, CT. This position will conduct experiments with FACS and flow cytometry to support our drug discovery efforts for biologics. This individual will be expected to make major contributions to the generation of best-in-class and first-in-class therapeutics to address major unmet medical needs.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities:

  • Initiates and completes routine procedures in an independent and efficient manner; Troubleshoots effectively and solves scientific problems; Operates lab equipment and is independently responsible for maintenance; Interprets and analyzes technical data accurately and independently.

  • Independently applies basic scientific principles, performs literature searches, attends scientific meetings, and keeps abreast of literature in own field.

  • Proposes and implements new technologies to improve process quality and efficiency.

  • Effectively communicates orally and in writing; Discusses own work in the context of team and department goals in a concise and accurate manner; Drafts and audits technical reports and contributes to writing of publications.

  • Reports and treats data with a high level of integrity and ethics.

  • Complies with applicable regulations, performing all work in a safe manner; Maintains proper records in accordance with SOPs and policies. 

Scientist III Requirements:

  • Master’s Degree from an accredited institution with three-plus (3+) years of experience in related scientific discipline, OR Bachelor’s Degree from an accredited institution with seven-plus (7+) years of experience in related scientific discipline or equivalent experience in related field

Scientist IV Requirements:

  • Master’s Degree from an accredited institution with six-plus (6+) years of experience in a related scientific discipline, OR Bachelor’s Degree from an accredited institution with 10+ years of experience in a related field or equivalent experience in a related field

Requirements for both levels:

  • Extensive hands-on experience with flow cytometry (minimum of 5 colors) including design, acquisition and analysis.

  • Experience with multi-parameter FACS sorting preferentially on BD flow cytometers (LSRII, LSR Fortessa, Canto, Aria) is preferred.

  • Experience with isolating and phenotyping primary immune cells using flow cytometry

  • Experience with magnetic cell separation systems for the isolation and purification of cells from heterogeneous populations.

  • Experience with immortalized and primary cell culture techniques is preferred.

  • Experience with the design and implementation of cell-based assays is preferred.

  • Experience with high-throughput flow-cytometry assay workflow is preferred.

  • Thorough and demonstrated understanding of commercial flow cytometry software including Flow Jo and BD FACS Diva.

  • Experience in use of Microsoft Office tools and GraphPad (Prism)

  • Background knowledge of general biotherapeutics discovery processes, including lead generation, protein science, biophysical and biochemical characterization is preferred.   

  • Ability to work within a collaborative team environment, present and defend results to project and technical teams.

 

Eligibility Requirements:

 

Must be legally authorized to work in the United States without restriction.

Must be willing to take a drug test and post-offer physical (if required)

Must be 18 years of age or older

 

Who We Are:

 

At Boehringer Ingelheim we create value through innovation with one clear goal: to improve the lives of patients. We develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company we focus on long term performance. We are powered by 50.000 employees globally who nurture a diverse, collaborative and inclusive culture. Learning and development for all employees is key because your growth is our growth.

 

Want to learn more?  Visit boehringer-ingelheim.com and join us in our effort to make more health.  Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities. All qualified applicants will receive consideration for employment without regard to a person’s actual or perceived race; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.

Job Research & Development
Primary Location Americas-United States
Organization US-BI Pharma/BI USA
Recruiter Rebecca O'Brien

 

Apply

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Posted February 2,2021

Senior Principal Scientist, Flow Cytometry Lead, Discovery Technologies

Loxo Oncology

New York, NY

Position Summary:

Loxo Oncology at Lilly conducts discovery research, clinical development and regulatory affairs for oncology, with the goal of creating a pipeline of therapies that have the potential to make a meaningful difference for patients. Loxo Oncology at Lilly was created in December 2019, combining the Lilly Research Laboratories oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. The unit has team members in Boulder, CO, Indianapolis, IN, New York City, NY, South San Francisco, CA, San Diego, CA, Stamford, CT, and Madrid, Spain.

 

The leader of the Flow Cytometry Group, Discovery Technologies will be joining a dynamic group focused on executing experiments on the cutting edge of pharmaceutical sciences. This individual will be responsible for overseeing the flow cytometry core group where they will deliver flow data, and support the various research programs for identified targets. They will be expected to demonstrate expertise with flow cytometry experiments (multi color flow cytometry, cell sorting), as well provide flow cytometry training to other group members. The leader of the Flow Cytometry Group will be responsible for oversight of the flow cytometry facilities at Loxo including instrument maintenance and related upgrades. They will also be encouraged to develop their own ideas and contribute these to the broader group. The leader is expected to be a dynamic and motivated scientist who can drive their own experiments and research activities, while collaborating extensively with the rest of the organization to execute on various research programs.

Roles and Responsibilities of the Position
  • Scientific roles and responsibilities:

  • Oversee the flow cytometry facility and staff

  • Design and execute studies using flow cytometry; oversee experimental designs and execution

  • Undertake multi color flow cytometry and cell sorting experiments

  • Provide flow cytometry training to other group members as needed and desired

  • Work collaboratively with the clinical biomarker team to perform to support retrospective and exploratory efforts for clinical programs

  • Oversee equipment in the flow cytometry group, including maintenance and upgrades as needed

  • Provide scientific expertise on flow cytometry to rest of R&D organization

  • Interrogate experimental conduct of third parties/vendors

  • Train and oversee junior scientists in the flow cytometry core

  • Additional responsibilities:

  • Communicate results at project team meetings, be involved in the coordination and preparation of presentations

  • Discuss results with technical as well as non-technical personnel

  • Work in cross functional environments via extensive collaboration with other parts of the organization

  • Report results in formal documents for internal and external submission

  • Maintain meticulous and accurate laboratory notebooks with timely entries

Required Qualifications and Background
  • PhD in biological sciences with 3-5 years of experience, preferably in a pharmaceutical company or biotech and/or leading a core flow cytometry facility

  • Extensive expertise in flow cytometry work with at least 12 color panels

  • Ability to establish flow panels to address portfolio programs (heme and solid tumor cell surface markers, intracellular protein staining)

  • Strong expertise in data analysis (FlowJo, FACS Diva etc..)

  • Deep expertise in cancer disease states (indications, mutational status, tumor cell drivers)

  • Demonstrated experience in working collaboratively across various scientific disciplines to meet end goals of business

  • Leadership experience in a flow cytometry lab

  • Excellent communication and interpersonal skills

  • Demonstrated ability to succeed in a fast-paced environment, working on multiple projects with constantly changing priorities and deadlines

  • Excellent written and verbal communication skills

Physical Demands / Travel

 

TBD <5%. The physical demands of this job are consistent with working in a lab.

 

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

 

Work Environment

 

This position’s work environment is in a lab. 

 

The work environment characteristics described here are representative of those encountered by an employee while performing the essential functions of this job.

 

*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

 

Loxo Oncology, Inc. is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Apply 

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Posted January 26, 2021

Project Manager, Laboratory R&D

ICON Laboratory Services

Farmingdale, NY

At ICON, it's our people that set us apart.

This is an exciting opportunity to become join Project Management for the Research and Development department of ICON Specialty Labs. The Project Manager will lead multiple, consecutive, cross-functional teams to ensure that assigned projects proceed on time, within budget, and to the client's satisfaction. Working collaboratively with Clinical Development, Business Development, Client Services, Clinical Laboratory, Production, Quality and Regulatory, the Project Manager will help prepare responses to RFP's, timelines and budgets, and will also manage project communication with the client following receipt of the business.

The role

  • Plan, implement, and maintain detailed project timelines using Microsoft Project software

  • Organize project teams by conducting regular meetings with agenda, minutes and action items

  • Prepare, edit, and update project documentation (i.e., required deliverables, reports, agendas, minutes, tracking sheets, etc.)

  • Work collaboratively in a team environment with a spirit of cooperation

  • Manage multiple development projects in a dynamic, high-paced environment

  • Develop and integrate operational cross-functional project plans, ensuring successful execution of those plans

  • Ensure adequacy of project resources with department heads

  • Resolve issues and conflicts within and outside of project teams

  • Regularly report project status and issues to Senior Management and other stakeholders

  • Coordinate and develop program goals, strategic plans, and project budgets

  • Display excellent communication skills, including effective presentation, persuasion, and negotiation skills required in working with customers/coworkers while remaining calm and courteous under pressure

What you need

  • Bachelor's degree or local equivalent in Science, Business or related Field

  • Prior experience with flow cytometry/immunology in a lab or school setting

  • Working familiarity with Word, Excel, PowerPoint

  • Strong communication skills

Why join us?

Ongoing development is vital to us, and as a Project Manager, Labs you will have the opportunity to progress your career, with the potential to move into other related areas to enhance your skill set. Our benefits package is competitive, our scope is international and we genuinely care about our people and their success.

ICON is an equal opportunity employer and committed to providing a workplace free of any discrimination or harassment.

EOE race/color/religion/sex/sexual orientation/gender identity/disability/vet/national origin

Interested individuals should forward their CV to:

Thomas W. Mc Closkey, Ph. D.

Director, Global Research and Development

ICON Laboratory Services

thomas.mccloskey@iconplc.com

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Posted December 22, 2020

Flow Cytometry Specialist

Columbia University

New York, NY

 

The Columbia Center for Translational Immunology (CCTI) at Columbia University Irving Medical Center is a multi-departmental, multidisciplinary research center aimed at optimizing translation of advances in basic immunology from the laboratory to the clinic, understanding immunological diseases and events in humans and optimizing transfer of information and methodologies to achieve synergy between different disciplines of applied immunology.  The CCTI Flow Cytometry Core provides training and access to state-of-the-art flow cytometry instruments for biomedical investigators. The Core operates at two sites (CCTI and Cancer Center) and is equipped with 5 analyzers (LSRII, Fortessa, CantoII) and 4 cell sorters (Influx and AriaII). It also operates an Aurora spectral flow cytometer.

 

The Flow Cytometry Core is recruiting a flow cytometry operator at the level of Staff Associate. Responsibilities include: perform routine cell sorting for user; maintenance, quality control and trouble shooting of analyzers; ensure compliance with safety and regulatory requirements, provide scientific advice on experimental planning and troubleshooting; performs additional related duties as assigned.

 

Minimum Qualifications:

Requires a master’s degree in biology or related subject and at least one year of laboratory experience, or a bachelor's degree in biology or related subject and at least 4 years of related experience or equivalent in education, training and experience. The candidate selected for this position is required to undergo a drug screening test prior to a final offer of employment being made.

 

Additional Qualifications:

The desired candidate must be detail-oriented; possess excellent interpersonal, organizational and communication skills. Must be able to multi-task, maintain confidentiality, think creatively, work well as part of a team, and work well under pressure.

Experience with flow cytometry required. Experience with BD instruments and software (Diva) highly desirable. Knowledge and bench experience in the field of immunology, stem cells and/or hematology desirable.

 

To apply:

Please send cover letter, CV and list of references by email to the Core Director, Dr. Remi Creusot at: rjc2150@columbia.edu