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Posted Feb 23, 2023

 

Principal Scientist - Oncology and Cell Therapy Flow Cytometry

Takeda

Boston, MA

​

Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

Job Description

The Flow Cytometry team within Clinical Biomarker Sciences and Operations (CBSO) department in the Precision & Translational Medicine (PTM) function at Takeda Oncology is seeking a highly motivated scientist to join our translational flow cytometry efforts for bringing novel medicines to cancer patients worldwide. This team is accountable as a subject-matter experts to ensure high-quality data generation of flow cytometry-based biomarker assays in all phases of clinical development in oncology/cell therapy at Takeda. The selected candidate will be responsible for building in-house capability as well as overseeing CROs for flow cytometry assay development, fit-for-purpose validation, and clinical sample analysis. The selected candidate must have strong background in multi-parameter flow cytometry, immunology, and translational sciences, for data quality assurance generated internally and externally as well as providing technical insights to translational and operational teams at Takeda.

Position Accountabilities

• Conduct and oversee all aspects of conventional and spectral flow cytometry assay method development, validation, tech transfer, sample analysis and troubleshooting in clinical trials across Takeda oncology portfolio.

• Oversee and interact with CROs to ensure qualities and timelines of outsourced flow cytometry assays.

• Build in-house flow cytometry capability and perform experimental works to general high-quality data.

• Communicate with project teams to understand scientific needs as well as update technical progress and data interpretation.

• Able and willing to train other team members as required.

• Help explore and test novel flow cytometry technologies and data analysis platforms.

Education, Experience, Knowledge And Skills

• PhD in biochemistry, biology, medical technology, immunology, oncology, or similar.

• 5+ years of post-PhD work experience in immunology, oncology, or a related field.

• 2+ year work experience in pharmaceutical or biotechnology companies.

• Immunological knowledge covering phenotyping of multiple subpopulations of cells.

• Laboratory experience and understanding of high-dimensional flow cytometry biomarker assay development, fit-for-purpose validation, and clinical sample implementation.

• Theoretical and practical understanding of flow cytometry with experience to design and execute 15+ color flow cytometry panels.

• Considerable experience in the use of flow cytometry analysis software.

• Expertise working with a variety of sample types including whole blood, PBMC, cell lines and single-cell suspension from tissue samples.

• Deep knowledge of clinical trials and understanding of the role of biomarkers in clinical studies.

• Excellent written, organizational, and interpersonal communications skills to update internal team members and stakeholders as well as interfacing with external vendors.

• Strong attention to details, timelines, and quality.

• Works successfully under pressure with tight timelines.

• Proven critical reasoning skills including the identification and resolution of complex problems.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

What Takeda Can Offer You

• 401(k) with company match and Annual Retirement Contribution Plan

• Tuition reimbursement Company match of charitable contributions

• Health & Wellness programs including onsite flu shots and health screenings

• Generous time off for vacation and the option to purchase additional vacation days

• Community Outreach Programs

Base Salary Range 143,500.00 to 205,000.00. Employees may also be eligible for Short Term and Long-Term Incentive benefits. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.

The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

Empowering Our People to Shine

Discover more at takedajobs.com

No Phone Calls or Recruiters Please.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Apply here.

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Posted Feb 15, 2023

 

Senior Scientist, Flow Cytometry

Pfizer

Pearl River, NY

​

Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

 

What You Will Achieve

As a Senior Scientist, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be recognized as a technical expert and a scientific contributor. With your deep knowledge of the discipline, you will be an active team member whose decisions impact the project. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience. You will be forecasting and planning resource requirements for your project team.  Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide team members.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

 

How You Will Achieve It

• Regularly contribute and influence at the project team level.

• Effectively collaborate with other members of Vaccine Research & Development and supporting partner lines.

• Develop, optimize, and perform FACS-based and other biomarker assays to support preclinical and clinical studies.

• Conduct cell-based immunoassays on preclinical and clinical samples in accordance with Good Clinical Laboratory Practices (GCLP) requirements.

• Develop assays or animal models required to support various vaccine projects.

• Develop tool assets for advancing systems biology group projects

• Supervise colleagues in design and execution of experiments.

• Identify, trouble-shoot, and optimize relevant assay systems, technologies, and readouts.

• Conduct research that leads to publication in peer-reviewed journals and presentation of data at internal and external meetings.

 

Qualifications

 

Must-Have

• Bachelor's Degree

• 9+ years of experience

• Expertise and hands-on experience with mammalian cell culture, flow cytometry/FACS

• Experience in immune cell isolation and characterization using multi-color flow cytometry

• Broad experience in assessing T cell function

• Technical knowledge of vaccine biology

• Ability to perform complex data analysis

• Excellent oral and written communication skills

 

Nice-to-Have

• Master's degree and 7+ years of relevant experience

• Extensive experience in vaccine research, innate immunology, or related fields, and a desire to continue in a laboratory-focused role

  

Work Location Assignment: On Premise

​

Relocation assistance may be available based on business needs and/or eligibility.

 

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment.  As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

​

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

 

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.

​

Link to apply.

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Posted Feb 2, 2023

 

Scientist II

FlowMetric, a KCAS company

Doylestown, PA

​

FlowMetric, a KCAS company, is looking for a dynamic Scientist II to join our dedicated team of scientists who focus on Client Service and Quality, located at our laboratories in Doylestown, PA. The ideal candidate will be motivated, energetic, forward thinking, and possess outstanding technical skills, organizational awareness, and a commitment to excellence in their work.

 

The Scientist II position is an integral team member role and is directly responsible for the preparation, conduct and analysis of experiments that contribute to the successful completion of scientific projects in the laboratory in a high quality and efficient manner. 

 

The Scientist II will follow complex flow cytometry projects from inception to completion and will become a key data provider to support the Director. 

 

The Scientist II will be expected to contribute intellectually to the progress of the project while acting as a mentor to peers in a supportive manner when necessary. 

 

In this role, we will rely on you for the following:

 

• Responsible for the design and execution of laboratory worksheets for complex flow cytometry preclinical and clinical studies.

• Responsible for performing all laboratory activities in accordance with GLP and GCP.

• Responsible for revising and following SOPs.

• Responsible for the execution of experiments for client sponsored projects.

• Able to undertake projects through to completion while working on other projects at different stages.

• Able to create project data summaries and presentations/ reports according to company standards.

• Proficient on all relevant equipment.

• Have a working knowledge of Microsoft Office including PowerPoint, Word, and Excel applications.

• Assist Director in communications directly with client either by email or in meetings.

• Possess excellent time management skills, multi-tasking capabilities and strong organizational skills.

• Keep abreast of relevant literature to function in the position.

• Act as an advocate for FlowMetric at external meetings, external and internal functions when required.

• Performs any other duties as required or assigned.

• Perform all flow cytometry operations, including sample preparation, sample acquisition, data analysis, and presentation.

• Proficient on all equipment to include FACSARIA III and LSR Fortessa high-throughput, and any other equipment as required.

• Operate, maintain, calibrate and trouble shoot laboratory instruments according to SOPs.

• Develop client interactions and relationships.

• Operate as an integral team member in day-to-day laboratory operations.

• Use of FlowJo analysis software.

• Use of cell sorting and single cell isolation techniques.   

(This is a representative summary of responsibilities and is not meant to be exhaustive)

 

WHO YOU ARE:

You will thrive at FlowMetric if you enjoy a fast-paced environment, are open-minded and flexible, can prioritize effectively to solve problems and meet deadlines, embrace high-level performance and constant development, and are self-directed while being drawn to the camaraderie of a team atmosphere.

In addition, to qualify specifically for this role, you will have:

 

Education and Experience:

• Minimum of a Bachelor’s degree in a scientifically related discipline with at least 3 years of prior industry experience in immunology/ cell biology/ flow cytometry (Master’s in Science preferred). 

• Experience with Becton Dickinson cytometer instruments preferred. 

• Prior flow cytometry experience required. 

• Familiarity with FACSDiva software and FlowJo Software. 

• Experience in a GLP laboratory environment preferred.

Knowledge, Skills, and Abilities:

• Genuine interest in learning.

• Open to real-time feedback.

• Excellent communication skills.

• Accuracy and attention to detail.

• Reliability and consistency in work effort.

• Commitment to quality, safety, and customer satisfaction.

• Solid mathematical abilities

• Perform all aspects of job in a way that supports company brand and supports company mission, vision, and values. 

Physical Requirements:

• Ability to lift 20 pounds.

• Ability to sit or stand for extended periods of time.

• Ability to convey complex information clearly and concisely.

• Ability to ascend and descend stairs.

 

WHAT YOU’LL GET:

In addition to a competitive compensation, full suite of medical benefits and time off, you will have the opportunity to be part of employee appreciation events and local community outreach. You’ll thrive in a fast-paced environment centered on career progression and development, where we collaborate on impactful contributions and reward for outstanding performance.

 

WHO WE ARE:

FlowMetric, a KCAS company, is a global Contract Research Organization with over a decade of proven scientific success. We are driven by the mindset that scientific excellence should deliver decision-enabling data on programs that matter the most to you. Our mainstay is cellular analysis; flow cytometry and single-cell proteomics are our platforms of choice.

KCAS is a contract research organization (CRO) headquartered within the metro area of Kansas City, KS. We are uniquely positioned to provide our pharmaceutical clients with both large and small molecule development in support of drug developments, preclinical and clinical studies. Demand for our expertise in bioanalytical & biomarker services is growing and so is our team of dedicated experts - now is a great time to join us to be part of improving the world’s health!

FlowMetric and KCAS are proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity or any other legally protected category.

​

LIMITATIONS AND DISCLAIMER

The above position description is meant to describe the general nature and level of work being performed; it is not intended to be construed as an exhaustive list of all responsibilities, duties, and skills required for the position.

This position description in no way states or implies that these are the only duties to be performed by the employee occupying this position. Employees may be required to follow additional instructions and to perform other duties as directed by a supervisor. Requirements are representative of minimum levels of knowledge, skills and/or abilities. To perform this job successfully, the employee must possess the abilities or aptitudes to perform each duty proficiently. Continued employment remains on an "at-will" basis.

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Any candidates can apply online here.

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Posted December 20, 2022

 

Staff Scientist – Flow Cytometry

Yale University - West Campus Flow Core

Orange, CT

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77953BR

Candidates should apply here: https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?partnerid=25053&siteid=5248&PageType=JobDetails&jobid=1570662

 

 

Position Focus:

Provide technical flow cytometry support in an existing comprehensive analytical instrumentation facility at Yale West Campus.

 

Instruct faculty, graduate student, and postdoctoral researchers in the use of various flow cytometry instruments. Maintain several flow cytometers including two cell sorters (BD FACSymphony S6 and BD FACSAria) and two cell analyzers (Cytec Aurora and Stratedigm S1000) along with the associated computer systems and network. Being responsible for the day-to-day operations of the Core including managing and expanding the user base.

 

The staff scientist will create a collaborative and engaged user community and contribute to the broader research mission of the campus.

 

Dept/Section URL

Click here for more information

 

 

Required Education and Experience

Bachelor's Degree in a related field and five years of related experience in a research development facility or an equivalent combination of education and experience.

 

Required Skill/Ability 1:

Broad knowledge and hands-on training in the theory and practice of flow cytometry, including with cell sorting and cell analyzer flow cytometry instruments.

 

Required Skill/Ability 2:

Strong communication skills and ability to effectively train users and staff on proper procedures and methods for using flow cytometry as well as processing and interpreting resulting flow cytometry data.

 

Required Skill/Ability 3:

Demonstrated skill and understanding of state-of-art flow cytometry including the ability to provide technical support for collaborative design and execution of modern flow cytometry methods.

 

Required Skill/Ability 4:

Mechanical and electronic skills relevant to maintenance, repair, and modification of scientific instruments. Computer skills for instrument operation and data analysis.

 

Required Skill/Ability 5:

Good interpersonal and communication. Skills to facilitate working with faculty and students to assist them in operating instruments and interpreting data.

 

Preferred Education, Experience and Skills:

PhD in Chemistry, Biology, or related field. Proven ability and experience to operate and maintain various flow cytometers, including cell sorters (BD FACSymphony S6 and BD FACSAria) and cell analyzers (Cytec Aurora and Stratedigm S1000), as well as associated computers and software (e.g. FlowJo). Prior experience working in and/or overseeing a multi-user flow cytometry facility.

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Posted December 9, 2022

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50550-LVL ICF TRC Flow Cytometry Manager

SSi People

Lawrenceville, NY

​

Our client is looking for a candidate who will provide flow cytometry laboratory support to their Immunoscience Drug Discovery group and to the Translational Research groups within the Immunology, Cardiovascular, and Fibrosis (ICF) Thematic Research Center (TRC). The candidate should possess the technical knowledge to setup, maintain, and troubleshoot both traditional and full spectrum analyzers and sorters. The candidate should also be knowledgeable with various flow cytometry analytical concepts and familiar with performing the analysis on a variety of analytical applications, such as FlowJo, Cytobank, and/or FCS Express. The candidate must have a deep understanding of flow cytometry concepts, such as panel design and optimization, compensation/spectral unmixing, and cellular sorting. The candidate must be an organized, detail-oriented, and a self-directed individual who can handle a variety of flow cytometry-related tasks in a matrix environment.

 

Representative responsibilities will include, but are not limited to:

·       Flow cytometry support, daily QC, monthly maintenance, vendor service and preventative maintenance scheduling, instrument standardization, database management, and user training on BD, Sony, Cytek, Miltenyi, and Amnis instruments

·       Assist researchers in experimental design and execution of flow cytometry experiments

·       Including but not limited to:

·       Panel design and optimization

·       Cell isolation, sample preparation and staining

·       Data Acquisition

·       Cellular Sorting

·       Data analysis and presentation

·       Develop and review flow cytometry laboratory procedures and SOPs for Customer review and approval

·       Maintenance of laboratory stocks of supplies and reagents at Customer’s expense

·       Interface with Unity Lab Services on systems’ contract coverage, preventive maintenance, service calls to minimize system downtime and optimize performance

·       Regular communication with ICF TRC on the usage, status, and performance of flow cytometry instrumentation

 

Minimum requirements:

·       5 to 8+ years working in a biology or flow cytometry lab in a research environment.

·       Previous experience managing laboratory flow core preferred.

·       BS/MS in scientific discipline preferred, but not necessary.

·       Must possess excellent organization skills and have a high attention to detail with a desire to get the job completed accurately and in a timely manner.

·       Must be collaborative and a team player, resourceful and take initiative.

·       The position requires strong interpersonal skills and exceptional communication skills (both verbal and written).

·       Ability to exercise independent discretion and judgment to solve problems is essential.

·       Strong analytical and computer skills, including expertise in using Microsoft Word, PowerPoint, Excel, Outlook, and SharePoint are required.

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Posted November 2, 2022

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Flow Cytometrist

NYU Langone

New York, New York

 

We have an immediate opening in our busy core facility for a flow cytometrist with experience operating cell sorters. Responsibilities for this position include daily operation of cell sorters, assistance with experimental design and scheduling, and daily in-person interaction with investigators.   The successful candidate should be scientifically inquisitive, should be skilled in PC operation (Windows) , and  have excellent communication skills.

 

We have a diverse instrumentation fleet which can be viewed on our web page:

https://med.nyu.edu/research/scientific-cores-shared-resources/cytometry-cell-sorting-laboratory/instruments-services

 

If you , or anyone you know, has interest in working in a fast-paced cytometry laboratory in New York City, please forward a letter of interest along with your CV to Peter.Lopez@nyulangone.org.

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Posted November 2, 2022

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BD Biosciences

BD Biosciences Research Reagent Specialist

New York, New York

 

To Apply: Use the following link:

 

https://bdx.wd1.myworkdayjobs.com/EXTERNAL_CAREER_SITE_USA/job/USA-CA---San-Jose/Research-Reagent-Sales-Specialist---Flow-Cytometry---New-York_R-455082

 

R-455082 Research Reagent Sales Specialist - Flow Cytometry - New York

 

The BD Biosciences Research Reagent Specialist (RRS) is responsible to maintain and grow the current Academic, Pharma, Biotech, CRO, Clinical Research and Government customer base. Field based position. Geography includes: New York/CT.

Primary responsibilities include developing and crafting new business opportunities through promoting the reagent portfolio, working strategically with their Instrument Sales Specialist, scM, Custom Technology Team, Applications Specialists, Service Team and Distribution Representatives.  The RRS will actively seek to retain/develop our large key accounts and convert competitive business in assigned territory, with the intent of growing revenue while balancing reasonable margins. The RRS reports to the Area Sales Director (ASD) and is directly responsible for achieving their territory sales growth.

​

Responsibilities:

·       Meet routinely with customers, focusing on key accounts and large business opportunities.

·       Develop Territory Business Plan to achieve sales goals.

·       Use business systems and tools to optimally forecast monthly sales for key accounts and overall territory.

·       Run territory activities through Salesforce.com, including, but not limited to, supervising customer interactions, and pricing/quotation requests.

·       Develop and maintain adequate short/long term sales pipeline to consistently generate profitable revenue.

·       Achieve revenue goals by growing existing customer bases as well as conversions of competitive accounts.

·       Work with the Area Sales Director, Instrument Sales Specialist, and GLobal Key Accounts Leader to build growth business plans around Strategic Accounts.

·       Build team relationships with other BD Biosciences Associates, including Sales, Service, and Applications Support to improve sales revenues and promote        customer-focused system solutions.

·       Develop and maintain one-on-one relationship with key distributor sales reps within assigned areas.

·       Perform other related duties and assignments as the need arises.

​

Qualifications:

Required:

·       A minimum of a Bachelor's degree, in a scientific field.

·       A minimum of 2 years of experience in sales or other customer-facing position, preferably in the Life Sciences marketplace.

·       Hands on laboratory experience, highly preferred in flow cytometry.

·       A valid driver's license.

·       Ability to travel a minimum of 50% of the time.

·       Effective interpersonal, written and oral communications skills.

·       Effective organization and planning skills.

·       Effective selling and negotiation skills.

Strongly Preferred: 

·       BS Degree in Biology or other Medical/Life Sciences-related field

·       Familiarity with Life Science Research and Pharma/Biotech/Academic accounts.

·       Previous Flow Cytometry knowledge and working experience highly preferred.

·       Distribution experience a plus.

·       Solid understanding of automated biomedical instrumentation, computer technology, and reagents.

·       Ability to adapt to changing business environment and continually meet customer needs.

·       Effective meeting, training, and presentation skills.

·       Experience in managing both internal and external budgets and resources, conducting pre-call planning, and ability to prioritize and segment accounts.

·       Effective decision making/problem-solving skills.

·       Effective digital literacy, i.e., Outlook, Excel, Word, PowerPoint, SalesForce.com, etc.

​

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Posted October 2, 2022

​

Weill Cornel Medicine, Flow Cytometry Core Facility

Research Specialist

New York, New York

 

We are looking for a junior member to join our team.  No experience necessary.  We will train you to become a world class flow cytometrist.  At our facility we provide flow cytometry services, sorting and analysis, along with training and education for the Weill Cornell Medicine research community.

 

Position Summary

This position will provide cell sorting technical support for the Weill Cornell Medicine (WCM) Core Laboratories Center (CLC) Flow Cytometry Core Facility in New York City.  Responsibilities include operation of fluorescence activated cell sorting (FACS) and analyzer instruments, maintenance of flow cytometry equipment, quality control procedures, sample and process tracking, assisting researchers on the use of equipment and software.

 

 

Knowledge, Skills and Abilities

Experience in building successful relations with supervisors and fellow workers.

 

Ability to learn new software and comfortable tinkering with technology.

 

Experience working in a biomedical research preferred but not required.

 

Experience working with flow cytometry technologies, applications and analysis tools is preferred but not required.   

 

Bachelor’s degree in a related field.

 

 

For More details and to apply please contact Co-Directors:

 

Tomas Baumgartner and Jason McCormick

 

tob2008@med.cornell.edu, jam2073@med.cornell.edu

​

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Posted September 23, 2022

​

Dotmatics

Engineering Manager/Staff Engineer/Principal Engineer

Remote, US

​

TO APPLY FOR THIS POSITION EMAIL YOUR RESUME TO: michelle.laing@dotmatics.com

​

Dotmatics is a leader in R&D scientific software connecting science, data, and decision-making. Its enterprise R&D platform and scientists’ favourite applications drive efficiency and accelerate innovation. More than 2 million scientists and 10,000 customers trust Dotmatics to help them create a healthier, cleaner, safer world. Dotmatics is a global team of more than 800 employees dedicated to supporting its customers in over 180 countries. The company is headquartered in Boston, with 14 offices and R&D teams located around the world.

​

Dotmatics is backed by Insight Partners, a leading global venture capital and private equity firm investing in high-growth technology and software scaleup companies. Learn more about Dotmatics, its platform, and applications including GraphPad Prism, Geneious, SnapGene, Protein Metrics, and LabArchives at https://dotmatics.com.

 

Description

We are looking for an extraordinary Engineering Manager/Staff Engineer/Principal Engineer. You will have the opportunity to scale, mentor and support a growing engineering team, while applying your hands-on technical skills to help architect and lead product engineering initiatives for a rapidly growing, modern SaaS solution.

​

You will be working on an industry defining product, developing technology that improves humans life’s by supporting scientist in the creation of treatments for life threatening diseases. You will be passionate about creating scientific technologies that will define a generation.

As the Engineering Team Lead you will be developing user-friendly interfaces and visualizations for scientists, designing glorious APIs for both internal and external use, living the DevSecOps life and building seamless product integrations & mentoring a small buy mighty team are just a few examples of what you will be doing.

​

In this role you will get to:

• Manage, expand, and develop a product engineering team to support our growing needs

• Provide technical vision and strategy for the engineering team, driving decisions around new practices, technologies and tooling

• Architecting, proposing and implementing key technical solutions, contributing to development, ops, and associated activities

• Collaborating with product and business stakeholders, managing scope effectively against product priorities

• Collaborating with engineers to design and implement solutions

• Integrating best practices into product development

• Authoring technical documents that cover product and design needs

• Promote DevOps style collaboration and integration across the full stack: inclusive of development, testing, and systems operations

• Mentors junior engineers through formal and informal discussions, code reviews, design reviews, and technical presentations

• Manage cloud infrastructure to maintain our high standards in cloud cost efficiency

 

We are looking for people who have 10+ years engineering experience, and have lead teams in a complex cross function environment, you will have back end focus with a strong understanding of front end & be a hands on leader with a desire to develop solutions to complex engineering problems. Ideally you will have some domain experience in: flowcytometry – Cell samples / Analysis / Data Analysis / Visualization (graphing plotting) (Machine learning) and demonstrate

• Google Cloud Platform experience

• Proficiency in GoLang

• Working knowledge of Kubernetes

• Coding experience in:, Javascript / Angular / Familiar with RXJS / D3 / some scripting, R / Python would be nice

• C++ or java is helpful

• Working knowledge of Architecture

• Expert experience in object-oriented design, data structures, algorithm design, problem solving and complex analysis

• Expert experience Software engineering practices & best practices for the full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations

 

 

Dotmatics is an equal opportunity employer. We are a welcoming place for everyone, and we do our best to make sure all people feel supported and connected at work.

​

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Posted August 19, 2022

​

Bristol Myers Squibb

Senior Manager, Principal Scientist (Analytical Science & Technology, Cell Therapy Quality)

Seattle, WA; Summit,NJ or Devens, MA

​

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMS’s continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.

 

Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMS’s continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.

 

The Cellular Therapy Quality (CTQ) organization is seeking a Principal Scientist/Senior Manager who will be responsible for the quality oversight of Flow Cytometry methods in support of the Cellular Therapy product portfolio.

 

This position will report into the Analytical Science & Technology (AS&T) group within the CTQ organization. Successful candidates will have a strong foundation in multi-parameter flow cytometry assays and demonstrated experience working in a cGMP environment. 

 

Responsibilities:

·       Responsible for the stewardship of late-phase flow cytometry methods in the Quality organization.

·       Implement method lifecycle and method maintenance programs to support flow cytometry methods used in the release of cell therapy drug products.

·       Responsible for transfer and validation of methods from Development to Quality Control (QC) laboratories in compliance with global regulatory requirements.

·       Responsible for authoring relevant analytical sections of submissions, responding to health authority questions and representing the QC function during inspections.

·       Function as the flow cytometry technical expert for QC labs during internal QC investigations and as the Quality liaison with contract test labs during QC investigations.

·       Partner with development organizations in the design of development and qualification studies, selection and characterization of reagents, and method optimization initiatives. Represent the QC department on cross-functional project development teams.

Qualifications and Education Requirements

·       MS/PhD in relevant scientific discipline and 10+ years (or equivalent combination) experience in multi-parameter (>10-color) flow cytometry execution, training, and technical support. Experience in cellular therapies is preferred.

·       Strong scientific background and expertise with multiple flow cytometry platforms from analyzers to cell sorters.

·       Experience in analytical method lifecycle, including method transfer, validation and maintenance. Experience providing training in method execution as well as instrument operation and standardization. Experience with implementing flow cytometry methods in a commercial QC facility is preferred.

·       Experience in cGMP regulations and application within the Quality Control environment. Understanding of FDA, EMA, ICH, USP, and EP guidelines and regulations associated with the quality control of biological products.

·       Must possess effective time management skills, demonstrate initiative, resourcefulness and flexibility to work independently and as part of a team.

·       Strong technical writing experience (SOPs, Method Validation Protocols and Reports) is essential.

 

If you want to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here with our Cell Therapy team. Full of incredible and dedicated team members, those working on CAR-T and other forms of Cell Therapy are transforming patients’ lives through science. From studying individualized cell lines to making brand new discoveries, this bold and personal discipline allows you to grow your career while making a lasting impact on the field of medicine. Join us today.

 

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

 

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. 

 

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

 

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation.  Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment.  This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

 

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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https://bristolmyerssquibb.wd5.myworkdayjobs.com/BMS/job/Seattle---WA---US/Senior-Manager--Principal-Scientist--Analytical-Science---Technology--Cell-Therapy-Quality-_R1561127

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Posted August 12, 2022

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MIT – Koch Institute for Integrative Cancer Research

Technical Associate II, Flow Cytometry Core Facility, Full-Time

Cambridge, Massachusetts

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TECHNICAL ASSOCIATE II-FLOW CYTOMETRY CORE FACILITY, Koch Institute for Integrative Cancer Research, to provide support for over 160 groups engaged in cancer and other research across MIT.  Responsibilities include operating and maintaining flow cytometer analyzers and sorters, including daily quality control and data management; engaging with researchers to design experiments, training in instrument use, and supporting scheduling needs; performing complex tasks such as troubleshooting instrumentation, liaising with service providers, and data analysis; collaborating with team members on problem solving and technical and administrative tasks; sharing relevant information with those impacted by decisions or instrument downtime; communicating and training others on lab/departmental policies and ensuring compliance; maintaining a clean and safe work area; performing duties normally engaged in by those working at lower levels as necessary; and recognizing situations that are without precedent and finding solutions using a systematic approach.  May serve as facility EHS representative.

 

This position offers an exciting opportunity for someone who can use independent judgment and is interested in working in a dynamic, team-oriented laboratory setting.

 

Information about MIT’s Koch Institute for Integrative Cancer Research: https://ki.mit.edu

 

Working at MIT offers opportunities that just aren’t found anywhere else, including generous and unique benefits that help to ensure that MIT employees are healthy, supported, and enjoy a fulfilling work/life balance. We welcome people from all walks of life to bring their talent, ideas, and experience to our community. We value diversity and strongly encourage applications from individuals from all identities and backgrounds – like yours. If you want to be part of our exceptional, multicultural, collaborative, and inclusive community, then take a look at this opportunity.

 

REQUIRED:  B.S. degree in biological or physical sciences; at least four years of experience in a research laboratory environment; ability to work both independently and as part of a team; strong instrumentation skills; demonstrated attention to detail; self-motivation; excellent organizational, analytical, customer service, interpersonal and verbal and written communication skills; and an understanding of laboratory safety. PREFERRED:  experience with BD analyzers and BD or Sony high-speed sorters, and experience training individuals from diverse scientific/technical backgrounds. Job #21569

 

MIT is an equal employment opportunity employer. We value diversity and strongly encourage applications from individuals from all identities and backgrounds. All qualified applicants will receive equitable consideration for employment based on their experience and qualifications, and will not be discriminated against on the basis of race, color, sex, sexual orientation, gender identity, religion, disability, age, genetic information, veteran status, ancestry, or national or ethnic origin.

 

Application welcome at: https://careers.peopleclick.com/careerscp/client_mit/external/jobDetails/jobDetail.html?jobPostId=24876&localeCode=en-us

 

If you have questions please contact: Michele R Griffin (michelep@mit.edu)

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Posted August 10, 2022

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CellNetix Pathology & Laboratories

Flow Cytometry Technologist (ASCP)

Tukwila, WA

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ABOUT US

 

CellNetix Pathology & Laboratories is headquartered in the Seattle area in our state-of-the-art Central Processing Laboratory. As one of the largest AP labs in the United States, with over 300 staff members and 60+ distinguished Pathologists, we offer some of the most technologically advanced resources and service menus in the region. In addition, our cutting-edge Molecular Laboratory with next-generation sequencing offers groundbreaking personalized medicine testing. Our lab continues to grow in technology and scientific advancement while offering our employees a wide array of training and career progression pathways in Administration, Laboratory and Hospital Support, Histology, Cytology, Infectious Diseases, Molecular, Grossing and more. If our mission of patient care resonates with you, Come Grow with Us in Pursuit of Excellence.

 

Position Summary:

 

We are seeking a strong FLOW Cytometry tech to join our outstanding team in our state-of-the-art laboratory. The Flow Cytometry Technologist duties will include assay development, validation, overall test monitoring and troubleshooting. The position is responsible for accurate reporting of results, quality control, training new employees, equipment maintenance and all other duties assigned by the supervisor.

 

Position Schedule: Ideally 3rd Shift with schedule flexibility available. Ideal schedule options:

• Monday - Friday 5pm-1:30am or

• 3 days/week FT or PT.

• Weekend only available if preferred.

 

Qualifications and Experience:

• ASCP certification preferred

• 4-year degree in biological sciences/chemistry or completion of accredited laboratory program

• High-volume sample preparation and testing in a clinical bioscience laboratory

• Preferred: flow cytometry operation, troubleshooting and maintenance in a work environment

 

Benefits

 

CellNetix offers comprehensive benefits plan in addition to competitive pay. Some of the most popular benefits include:

• Free parking onsite

• Generous company paid healthcare (medical, vision, dental, prescription) plan options.

• Substantial 401K company match.

• Starting paid time off accrual of up to 15 days/year plus 8 paid holidays.

• Life and disability insurance.

• Fully subsidized ORCA card and free parking at most sites.

• Our most recent benefit addition of Norton LifeLock Identity Protection at no employee cost.

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IMPORTANT NOTICE: As a healthcare organization we are committed to providing a healthy and safe environment. We require a criminal history background check and drug test for all final candidates. Additionally, CellNetix has a mandatory COVID-19 vaccination policy.

See full job description here and APPLY!

Please contact recruiting@cellnetix.com for more information.

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Posted August 8, 2022

Updated October 18, 2022:  Still accepting applications for experienced or entry level candidates.

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Princeton University

Research Specialist I/II (Cytometry Specialist I/II)

Princeton, New Jersey

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A full-time Cytometry Specialist I/II position is available in the Flow Cytometry Resource Facility (FCRF) laboratory in the Department of Molecular Biology at Princeton University. The FCRF provides support for Princeton University faculty and student research utilizing state-of-the-art flow cytometry and fluorescence-activated cell sorting (FACS) techniques and instrumentation. We currently support over 35 Principal Investigator labs on campus working with a wide variety of model systems and assays. This is an excellent opportunity to join our shared resource lab and to develop/expand career skills in a growing field. Position level and salary commensurate with experience.

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This position reports directly to the Flow Cytometry Resource Facility Director. Cytometry Specialist I specific duties include:

 

• Assist with and carry out routine single color and advanced multi-color flow cytometry experiments with users (students, research staff, post-docs and faculty) on analytical flow cytometry instruments.

 

• Orient new users to the lab and directly contribute to the successful daily operation of the facility with minimal direction.

 

• Upon demonstration of appropriate knowledge base, training to operate several cell sorters will be provided with the goal of independent execution of a wide variety of FACS sorting experiments in a BSL2+ level facility.

 

• Provide instrument and software training to new and established clients with minimal supervision. The lab is equipped with Cell Sorters: BD FACSAria Fusion, Sony Biotechnology MA900, BioRad S3e, UnionBiometrica BioSort; Flow Cytometers: BD FACSymphony A3, BD LSRII; Others: Z2 Particle Counter, CytoSpin Centrifuge and FACSDiVa, FlowJo, & FCS Express software platforms.

 

• Provide technical assistance and consultation to clients on experimental design, including appropriate sample preparation techniques and necessary control samples.

 

• Perform daily quality control checks on the benchtop flow cytometers and cell sorters. Keep accurate, legible records to monitor instrument performance. In concert with Facility Director, complete scheduled and unscheduled system maintenance as needed.

 

• Assist in maintaining instrument/experiment calendars and become expert in the use of iLab scheduling and usage reporting software.

 

• Have the ability to multi-task in a fast-paced multi-user research environment while maintaining excellent attention to detail.

 

• Troubleshoot instrument and assay performance, assisting researchers with optimizing their experiments and data analysis.

 

• Archive all facility data and maintain workstation computers monthly.

 

• Organize and maintain a resource reference library for users.

 

• Perform routine laboratory duties including ordering of lab supplies with comparison cost sourcing, general lab upkeep, preparation of reagents, disposal of laboratory waste, and routine maintenance of laboratory equipment, including weekly sterilization and monthly cleaning protocols. Must be able to lift 50 pounds.

 

• Other duties as assigned by the FCRF Director.

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Cytometry Specialist II duties include all items outlined above plus: Independent operation of several cell sorters to successfully execute a wide variety of FACS sorting experiments in a BSL2+ level setting; knowledge of and adherence to standard cell sorting biosafety practices; interfacing with vendor service engineers; assisting in creating and editing facility standard operating procedures (SOPs) and training materials.

 

Essential Qualifications: Bachelor's degree in biology, biochemistry, cell biology, genetics, biotechnology or related field is required. The candidate should have:

 

• Strong interpersonal and communication skills, both written and verbal. This position requires constant interaction with a large user base of varying personalities and experience, so patience, willingness to teach and troubleshoot, and the ability to interact in a professional and effective manner is critical for success.

• Independent critical thinking and problem solving ability. Successful instrument troubleshooting, which is a major component of this position, requires implementing a logical deductive workflow, based on knowledge of flow cytometry principles and instrument components, to discover root causes and resolve issues.

• Flexibility and excellent attention to detail.

• Aptitude for continued learning and development, especially with regard to complex instrumentation and technology.

• Experience in a fast-paced, multi-tasking environment and the ability to work independently is required.

• Advanced knowledge of Microsoft suite (Word, Excel, PowerPoint) software is essential.

• For Cytometry Specialist II level: a minimum of 3-5 years of hands-on analytical flow cytometry and/or cell sorting experience; knowledge of standard cell sorting biosafety practices; and demonstrated knowledge of FACSDiVa and FCS Express or FlowJo software platforms.

 

Preferred Qualifications: Cytometry Specialist I: Previous flow cytometry knowledge and hands-on experience with routine and advanced multi-color experiments and cell sorting is desirable. One to three years’ work experience in a laboratory environment is preferred. Cytometry Specialist II: Hands-on experience and proficiency with the operation and maintenance of current instrumentation in the FCRF is preferred. Demonstrated experience with advanced flow cytometric data analysis and interpretation is desirable. Previous experience in a shared resource laboratory environment and in the training of new users is preferred.

 

Schedule: Monday-Friday, 9:30am-5:30pm. Please note that this position may require some flexibility of working hours, including occasional overtime to support research needs. No weekend hours are required.

 

The final candidate will be required to complete a background check successfully.

 

To apply, please visit https://careers.princeton.edu and use requisition # 2022-15279. Submission of a resume and cover letter is required.

 

Princeton University is an Equal Opportunity/Affirmative Action Employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability status, protected veteran status, or any other characteristic protected by law. EEO IS THE LAW

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