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Posted April 25, 2024

Flow Cytometry Scientist

The Ohio State University

Columbus, Ohio

The Pelotonia Institute for Immuno-Oncology (PIIO) at OSUCCC – James

 

Seeks a Flow Cytometry Scientist for its Immune Monitoring and Discovery Platform (IMDP)

 

The PIIO Immune Monitoring and Discovery Platform (IMDP) at The Ohio State University (OSU) is seeking an innovative flow cytometry Scientist. The IMDP delivers cutting-edge technology to analyze the immune system’s response to cancer immunotherapy. IMDP flow cytometry resources include Cytek Aurora Spectral Cell Sorter, Cytek Aurora Spectral Analyzer, Cytek Northern Lights, and BD FACSMelody.

 

The successful candidate will:

  • Understand the operation of flow analysis and cell sorting devices in depth.

  • Apply a comprehensive knowledge of immunology systems to support immuno-oncology (IO) investigators in achieving the best outcomes and understanding their findings.

  • Possess the necessary education and/or experience to work autonomously, act as a resource for users, train newcomers, and assist self-operators with instrument issues.

  • Have at least two years of experience with one or more of the following instrument systems: Cytek Aurora Spectral Cell Sorter, Cytek Aurora Spectral Analyzer, Cytek Northern Lights, and BD FACSMelody (experience with other instruments may also be acceptable (e.g. BD Influx, BD FACS Aria/Fusion/S6, BD Symphony, ACEA Novocyte).

 

Preference will be given to applicants (1) with at least 5-10 years of experience in flow cytometry, (2) extensive experience with cell sorting and (3) proficiency in FlowJo and Omiq.  Applicants with less years of experience will be considered if they have substantive knowledge in spectral flow cytometry.

 

Job Duties include:

  • Instrument maintenance, standardization, and quality assurance:

    • Establish and/or modifies and/or implements Standard Operating Procedures for routine instrument maintenance and performance evaluation.

    • Perform instrument setup and acquisition of samples independently.

    • Perform calibration/alignment, maintenance, trouble-shooting, repair of cytometers and associated facility instruments.

    • Document instrument performance, maintenance, service, and corrective actions.

  • Cytometry training:

    • Provide training for technicians and investigators with respect to the basics of the technology, instrument startup/shutdown and maintenance, data acquisition and transfer, and data analysis as needed.

  • Experimental design and optimization:

    • Work together with the laboratory Director to advise investigators regarding experimental design and data analysis.

    • Educate core laboratory clients with respect to sample requirements for specific experimental goals.

    • Work with investigators to explore and optimize current and emerging techniques.

  • Core management:

    • Assess inventory and order supplies when needed.

    • Conduct operations of the facility within safety guidelines for instrument operation, as well as chemical and biological safety standards

    • Maintain reporting and billing, process costing and fee development, budget development and management.

    • Manage technical staff including training, tasking, goal-setting, development, and mentoring.

  • Continuing education:

    • Maintain technical currency, identify, and assess developing technologies, platforms, reagents, and methods. Import and deploy as appropriate.

    • Present novel assays and techniques to research group.

  • Assay development:

    • Work independently or together with other laboratory staff to design and optimize new analytical methods.

    • Work with Director to evaluate new and existing methods with respect to accuracy, precision, and reproducibility.

  • Data analysis:

    • Work independently or together with Director to establish analysis strategies for flow cytometry-based assays.

    • Evaluate new tools for data analysis and data reduction. Train and implement others as required.

Education:

  • Bachelor's Degree OR Master's Degree in Biological sciences or related discipline

 

Experience (Training and Coursework):

  • Proficient knowledge of immunology, genetics, and flow cytometry.

  • Demonstrated success training and supervising others.

  • Demonstrated experience analyzing data from flow cytometry platforms using specialized analysis software and reducing that data to figures suitable for scientific presentations (FlowJo, DiVa and Microsoft Office products (Word, Excel, PowerPoint) and other common tools).

  • Five (5) years of related experience, to include supervisory/management experience.

  • Specialized training (theoretical and practical) in the application and conduct of flow cytometry practices.

  • Training in bacteriological, viral, chemical, and physical safety.

  • Proficiency with Macintosh and PC computers and handheld devices.

  • Able to work safely in a BSL2 environment.

  • Able to safely work with lasers and high voltage.

  • Able to work independently.

 

To apply: Send cover letter, CV,  contact information for three references via email to James Fant at James.Fant@osumc.edu.

 

About Us:

The PIIO is a comprehensive bench-to-bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels (https://cancer.osu.edu/piio). Launched in July 2019 as part of a $102 Million pledge from Pelotonia (pelotonia.org), the PIIO represents Ohio State's commitment to grow the exciting area of immuno-oncology. Led by founding director and renowned immunologist Zihai Li, MD, PhD, the PIIO builds upon a rich portfolio of active investigator-initiated IO clinical trials being conducted at the OSUCCC – James.

 

Research in the PIIO centers on Systems IO (a systems-wide strategy to study the anti-cancer immune response holistically to discover the next IO breakthroughs and create effective cancer immunotherapies) and Translational IO (where we turn discoveries into new or improved cancer treatments and broaden the indications and patient populations that can be treated with cellular therapy). Our Immune Monitoring and Discovery Platform (IMDP) supports each center, providing comprehensive cell-based and molecule-based immunoassay services to support basic, translational, and clinical IO studies. The PIIO’s Immuno-Oncology Informatics Group (IOIG) provides data analytics for flow and mass cytometry, bulk and single-cell RNA-Seq, spatial transcriptomics and imaging, neoantigen discovery, and more.

 

The OSUCCC – James is a National Cancer Institute (NCI)-designated comprehensive cancer center, rated “Exceptional,” the highest rating given to cancer centers by the NCI; is one of only a few centers funded by the NCI to conduct phase I, II and III clinical trials on novel anticancer drugs; and includes the third-largest freestanding cancer hospital in the country. Ohio State is located in Columbus—a highly ranked, modern, affordable, friendly and diverse city. The Ohio State University is an EOE/AA/M/F/D/V employer.

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Posted March 27, 2024

Field Applications Scientist - Flow Cytometry (West Coast)

Slingshot

Emeryville, California, Hybrid

Description

 

Slingshot Biosciences is a growing life sciences company with a platform technology and paradigm-shifting mission to make synthetic cells the gold standard for all cell-based applications.  We currently have a suite of products to help standardize and optimize flow cytometry assays with our unique and flexible technology.  At Slingshot, we value diversity and believe that a variety of backgrounds and experiences leads to more innovative ideas and a better understanding of our customers. Passion is at the core of our values, and employees are encouraged to pursue their passions in their work and contribute to the company's overall mission.  We desire motivated team members who appreciate the freedom to be creative and think outside the box to solve problems.  We offer an environment where employees are empowered to take ownership of their work and to contribute new ideas.  In everything we do, we are dedicated to delivering top-quality products to positively impact patient care.

Slingshot Biosciences is hiring a Field Application Scientist to both generate data at our onsite facility in Emeryville, CA and support our customer base in the field. This role will require up to 50% travel around the Bay Area, Pacific Northwest and Southwest regions of the US. We offer a great opportunity to be involved in product development while also working in a customer-facing role that collaborates with internal teams including Sales, Product Development, and Marketing.

This role reports to the Associate Director of Field Applications and all responsibilities are performed under the direction of the Associate Director.

 

Responsibilities

  • Generate data to support our catalog portfolio and drive adoption in the market

  • Generate data for presentation at conferences and in publications

  • Verify and help resolve customer complaints with data generation as needed

  • Report product feedback and customer issues to drive product improvement

  • Partner with Sales to demo Slingshot products to prospective customers in a way that helps to develop the opportunity and build trust & credibility both internally & externally.

  • Represent Slingshot Biosciences at conferences, trade shows, and customer visits

  • Consult with customers on best practices and assay optimization with Slingshot products

  • Coordinate and support custom opportunities with sales representatives

  • Foster a positive team-driven work culture

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur as business needs change.

 

Requirements

  • Work on-site at Emeryville office, with up to 50% travel expected within defined territory

  • 7+ years experience in biotech industry

  • 5+ years experience running flow cytometry assays in the 8-40 color range

  • Ability to proactively troubleshoot and optimize flow cytometry data

  • Ability to work independently and take initiative on generating data

  • Ability to communicate data, findings, and challenges, effectively and professionally with peers and management

  • Ability to manage time in a role involving both bench work and field travel

  • Experience with both extracellular and intracellular staining protocols for flow cytometry

  • Working knowledge of flow cytometry best practices, instruments, and reagents

  • High adaptability and flexibility in a very fast-moving and growth-oriented environment

  • Willingness to learn about and promote Slingshot Bioscience products to customers

  • Experience supporting commercial organizations and processes, and ability to function in a trusted advisor capacity for our customers

  • Strong strategic, conceptual, and analytical thinking skills

  • Ability to build strong working relationships with cross-functional teams and stakeholders

  • Excellent organizational, project management, time management, and communication skills

  • A willingness to learn and improve in the role

  • Must have excellent English communication skills, both verbally and in writing

 

Preferred

  • Master’s with 7+ years of flow cytometry experience or Ph.D. degree with 5+ years of flow cytometry experience in Immunology

  • Experience in a Biotech startup

  • Strong public speaking & presentation skills

  • Experience with clinical flow cytometry assays

  • Experience in analytical development, process development, and/or quality control departments

  • High level of comfort with operational and strategic customer-facing conversations

  • Experience with customer training

  • Previous experience in a customer-facing pre-sales and support capacity

 

All listed requirements are deemed as essential functions to this position. However, business conditions may require reasonable accommodations for additional tasks and responsibilities.

We offer competitive salary and benefits packages and a dynamic work environment that encourages professional growth and development. If you are a highly motivated individual with a passion for start-up environments, please apply today! Our salary ranges are calculated by role and level. Your position within that range will be determined by your job-related knowledge, skills, experience, relevant education, and training/certifications. The base salary range for this full-time position is between $90,000 - $110,000 + commission + equity + benefits.

Apply here.

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Posted January 5, 2024

Business Development Manager, Biomarker Solutions

Champions Oncology

US Remote - Hackensack, NJ

This is a remote position.

 

About us

Champions Oncology is a technology-enabled research organization that leverages an end-to-end range of research and development solutions to improve the productivity of oncology drug development. Using computational and experimental testing platforms, Champions Oncology improves decision making for effective therapeutic development. Our team is passionate and self-motivated working together to accelerate the challenges of oncology drug development and ultimately improve patients’ lives around the world.

 

 

Job Overview

The Business Development Manager is a fast-paced, competitive role, responsible for identifying and developing new opportunities within our Biomarker solutions offerings. The BD Manager will work closely with the global business development team to present and promote solutions to potential clients including new accounts.  This will include generation of new business opportunities at new and existing accounts, with the objective of establishing long term, mutually beneficial business partnerships. The successful candidate will be a self-motivated, self-started and driven individual who is goal-oriented, methodical, tenacious, and can effectively interact with a team at all levels. Duties and responsibilities:

  • Achieves annual sales plan and sales targets for assigned accounts.

  • Engages in deep scientific discussions with clients about pipeline programs and key needs for clinical trial programs.

  • Maintains a strong scientific acumen and understands emerging technologies and platforms in flow cytometry, immunohistochemistry (IHC), next generation sequencing and plate-based assays.

  • Performs strategic, scientific, tailored hunting to increase client base in territory and within existing accounts

  • Provides appropriate guidance to client to align Champions products and solutions to their needs

  • Provides general intelligence on key competitors, and the clinical trial market.

  • Develops account plans and partnerships with key accounts.

  • Develops client call cycle to achieve objectives and sales plan; Follows up on leads.

  • Provides general intelligence on key competitors.

  • Sells the business unit’s capabilities and differentiation frameworks.

  • Sets and manages customer expectations.

  • Collaborates with companywide resources to achieve superior customer satisfaction.

  • Organizes and hosts client visits.

  • Uses CRM to manage internal communication and document territory and client information as required for the business unit.

  • Responsible for Opportunity Management and accurate pipeline forecasting.

  • Maintains frequent personal contact with clients.

  • Leads client presentations.

  • Supports an established client base where appropriate.

  • Required travel 25%+

  • Other duties as assigned.

 

 

Qualifications

Knowledge, Skills and Abilities

  • At least 1-2 years relevant experience working in and a deep knowledge of the oncology and immuno-oncology therapeutic area.

  • At least 1-2 years of relevant experience in business development or customer facing experience and an established network in the biopharmaceutical industry.

  • Knowledge of flow cytometry, IHC and next generation sequencing.

  • Knowledge of GCLP is a plus.

  • Relevant experience in business development or related experience and an established network in the biopharmaceutical industry.

  • Demonstrated success in identifying, evaluating, and identifying or executing business development deals and partnerships that have resulted in substantial impact.

  • Strong interpersonal, analytical, critical-thinking, verbal and written communication skills.

  • Highly developed organizational skills.

  • Self-motivated, attention to detail, and proven ability to work well on teams

  • Ability to manage difficult client and/or financial situations

  • Ability to differentiate Champions from competitors

  • Strong working relationship with internal Champions management and site leadership

  • Demonstrated ability to acquire and grow client base

 

 

Education and Experience

  • Doctorate in Biochemistry, Molecular Biology, or related field, or BS or MS with a minimum of 5 years experience in a clinical laboratory setting or specialty instrument sales

  • Advanced industry knowledge in biopharma and/or a CRO setting

  •  Demonstrated ability to acquire and grow client base

 

 

Physical Demands and Work Environment

  • Must be able to sit for long periods of time using a computer in a typical home office environment.

 

This description reflects management’s assignment of essential functions, it does not proscribe or restrict the tasks that may be assigned.  We celebrate diversity and are committed to creating an inclusive environment for all employees. 

Apply here.

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Posted December 4 , 2023

Flow Cytometrist

The Flow Cytometry Core 

Cold Spring Harbor Laboratory (CSHL)

Cold Spring Harbor, New York

Join Our Team as a Flow Cytometrist at Cold Spring Harbor Laboratory!

Are you passionate about advancing scientific research? The Flow Cytometry Core at Cold Spring Harbor Laboratory (CSHL) is seeking a dynamic and experienced Flow Cytometrist to join our innovative team. As a world-renowned research institution, CSHL provides a collaborative and cutting-edge environment for individuals looking to make a significant impact in the field of life sciences.

 

Job Responsibilities:

  • Conduct cell sorting and analysis using state-of-the-art flow cytometry equipment.

  • Design and optimize experimental panels for various research projects.

  • Troubleshoot instrument-related issues and ensure proper functionality.

  • Perform data analysis and interpretation to support ongoing research activities.

  • Provide technical training to fellow scientists, fostering a collaborative and knowledgeable community.

Requirements:

  • Education: Bachelor's degree (BA or equivalent) in a relevant scientific field.

  • Skills/Experience:

    • Proven experience in cell sorting techniques.

    • Inquisitive mindset and a passion for advancing scientific understanding.

    • Ability to work independently and collaboratively within a team.

    • Proficiency in computer operation for instrument control and data analysis.

    • Excellent communication skills to facilitate effective collaboration.

Advantages:

  • Career Development: Exceptional candidates will have opportunities to advance their career and may progress to a managerial position.

  • Cutting-Edge Environment: Work with cutting-edge flow cytometry technology and contribute to groundbreaking research initiatives.

  • Collaborative Community: Join a vibrant community of scientists dedicated to pushing the boundaries of knowledge.

 

How to Apply:

For immediate consideration, please apply online to the position found here: Position ID: 748

 

Environment:

Cold Spring Harbor Laboratory is a world-renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. Cold Spring Harbor Laboratory provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program.

 

We believe that science is for everyone. We have had researchers with a variety of backgrounds and believe in the importance of diversity, equity, and inclusion.

 

Compensation and Benefits:

Our employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our CSHL Benefits sites to learn more. The salary range for this role is $53,000- $75,000.   The salary range and/or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and/or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity).

 

CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status. VEVRAA Federal Contractor

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Posted October 19 , 2023

Staff Associate I

Department of Microbiology & Immunology

Columbia University Medical Center

New York, New York

The Department of Microbiology & Immunology is searching for a Staff Associate I (Core Facility Manager) to assist scientific staff and manage the operations of the Department of Microbiology and Immunology Core facility. The Staff Associate’s responsibilities will be to:

  • Manages the Core Facilities by providing routine maintenance of instrumentation, troubleshooting, technical expertise, and operational assistance to Scientific Staff.

  • Assists in experimental design and flow cytometry and microscopy experiments.

  • Provides training to staff on data analysis and instrument operation.

  • Works with the Finance Office to prepare monthly billing for fees for all core facility equipment.

  • Clear and prompt communications to users regarding facility issues

  • Excellent customer service attitude.

  • Other duties, as assigned.

 

Most work will be conducted during regular business hours; however, due to the nature of this research, some flexibility is desired.

 

Salary Range or Pay Grade:  $58,710 - $70,000

 

Minimum Qualifications: Bachelor’s degree in Science, Engineering, or related STEM field plus.

 

Other Requirements:

  • Knowledge of FACS software, instrumentation, and maintenance.

  • Understanding of basic scientific methods.

  • Must have expertise in good laboratory practices and bio-safety procedures for BSL2 and BSL3 laboratories.

 

Preferred Requirements: 4-6 years of related experience

 

Equal Employment Opportunity Statement: Columbia University is an Equal Opportunity Employer / Disability / Veteran

 

Pay Transparency Disclosure: The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting.

 

Apply at https://apply.interfolio.com/133271

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Posted September 27, 2023

Technologist-Flow Cytometry

New York Blood Center

New York, New York

 

Job ID 2023-5212

Category Technician

Minimum Rate USD $44.89/Hr.

Maximum Rate USD $52.82/Hr.

Work Location Type Physical

Overview

At New York Blood Center, one of the most comprehensive blood centers in the world, our focus is on cultivating excellence by merging cutting-edge innovation with diligent customer service, groundbreaking research, and comprehensive program and service development. Join us as we work towards meeting and exceeding the growing needs of our diverse communities, further our lifesaving strategic goals in a rapidly changing environment, and expand our impact on the local, national, and global communities we serve.

Responsibilities

This position performs stem cell enumeration and viability, as well as T cell enumeration and phenotyping on apheresis products, bone marrow, peripheral blood stem cells, and umbilical cord blood.

 

Responsibilities:

  • Perform multi-parameter flow cytometric stem cell and T cell analysis, including enumeration, phenotyping, and viability assays on apheresis products, bone marrow, tissue and umbilical cord blood.

  • Perform equipment maintenance as indicated by manufacturer, including instrument set up, calibration, cleaning, and quality control.

  • Lab procedures related to sample processing and preparation, testing, data acquisition, analysis, report generation, and maintaining complete and accurate records of all testing performed.

  • Ensure accuracy of tests performed with a strict adherence to the applicable laboratory SOPs.

  • Perform and properly document all quality control activities and instrument malfunctions.

  • Provide results and reports in a timely and accurate manner.

  • Perform accurate analysis of samples and entry of results into computer system.

  • Follow the applicable laboratory SOPs and remain competent in those procedures as well as enhance continuing education and skill improvement.

  • Trouble shoot and resolve technical problems.

  • Assist with writing, updating, and maintaining procedures related to Flow Cytometry.

  • Train current and new staff on flow cytometry procedures. Perform lymphocyte subset proficiency testing.

  • Work schedule will depend on laboratory workload and may require flexibility.

  • Provide on-call coverage if required, may include after-hours stay and occasional weekends.

  • Prepare reports.

  • Perform inventory management.

  • Attend conferences, seminars, workshops, etc. to meet continuing education requirements.

  • Any related duties as assigned.

  • Validation of new reagents (including lot to lot verification), assays, and FLOW panels.

Qualifications

Education:

Bachelor’s or higher degree in clinical laboratory technology, or

Bachelor's or higher degree from a program with a major in biology, chemistry, or the physical sciences, and an advanced certificate in clinical laboratory technology, or

Education and training sufficient to qualify for licensure as a Clinical Laboratory Technologist prior to 2009 as specified in NYS-ED Regulation 79-13.4.

Experience in Flow Cytometry

American Society for Clinical Pathology (ASCP) certification

 

Experience:

Minimum of one year of experience in a Clinical Flow Cytometry Laboratory.

NYSDOH Clinical Laboratory Technologist License

NYSDOH Restricted License in Flow Cytometry

 

Knowledge:

Basic knowledge of FDA and NYSDOH regulations and AABB and FACT standards.

Professional knowledge of basic laboratory supplies and equipment.

Working knowledge of computerized systems.

Basic understanding of quality control procedures.

Knowledge of a variety of software applications (Microsoft Office Suite, FlowJo, FACSuite).

 

For applicants who will perform this position in New York City or Westchester County, the proposed hourly salary is $44.89/hr. to $52.82/hr.  For applicants who will perform this position outside of New York City or Westchester County, salary will reflect local market rates and be commensurate with the applicant’s skills, job-related knowledge, and experience.

 

New York State License Technologist

0-2 yrs. $44.89 p/hr.

2-5 yrs. $45.42 p/hr.

5-10 yrs. $48.06 p/hr.

10 yrs. $52.82 p/hr.

Unless otherwise specified, all posted opportunities are located in the New York or Greater Tri-State office locations

Apply for this job online

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Posted September 27, 2023

Clinical Flow Cytometry Data Analyst

Regeneron

Tarrytown, New York

R22391 Temporary - Clinical Flow Cytometry Data Analyst 

We are seeking a Clinical Flow Cytometry Data Analyst to join our Precision Medicine team. Precision Medicine, a part of Early Clinical Development & Experimental Sciences leads biomarker strategy and execution from early concept studies through late development and is supported by Precision Medicine Strategy Leads, Precision Medicine Operations specialists, as well as quantitative analytical and companion diagnostics scientists. 

Flow cytometry continues to gain importance with regulators as an essential method in the development of personalized medicine. In this newly created role that resides within Precision Medicine, the individual would be primarily responsible for supporting analysis and review of clinical flow cytometry data acquired across various clinical studies and therapeutic areas. The role requires a solid, hands-on understanding of flow cytometry and will support data characterization from conventional and spectral cytometry platforms often from large multi-color panels. In this role, the individual would develop a pipeline to ensure high data quality, working closely with key internal stakeholders and vendors. The selected individual would be an important contributor to the Biomarker Assays and Quality team. This is an onsite role with participation in meetings and activities in Tarrytown, NY. 

As a Clinical Flow Cytometry Data Analyst, a typical day may include the following: 

  • •Review and analyze raw data (using various gating strategies) to identify irregularities and negative trends

  • •Contribute independently and in matrix teams to improve data quality from flow cytometry experiments

  • •Meet with key stakeholders and develop KPIs for assay quality, and periodically review assay quality data from varioussources on relevant clinical trials

  • •Support clinical biomarker strategy leads through data upload, workflow sharing, and other activities performedespecially through cloud platforms

  • •Support initiatives to reduce instrument and technical variation across assays and vendors

  • •Support the development of business process documents related to these activities

  • •Manage limited number of critical internal reagents especially supporting cytometry assays with monitoring ofconsumption and forecasting future needs

  • •Participate in cross functional meetings to support flow cytometry and other biomarker assay development,validation and assay quality initiatives

 

This role may be for you if: 

  • •Candidate must be detail-oriented, self-starter and possess both strong organizational and communication skills

  • •Able to multi-task and critically analyze and troubleshoot technical/scientific problems of various complexity levels

  • •Ability to collaborate cross-functionally with members of the Flow Cytometry Core and research therapeutic areas

 

To be considered for this role, you must have a B.S. with at least 2-3 years’ experience performing and analyzing flow cytometry assays or M.S. with at least 1 year experience. Experience and coursework in Immunology and/or Oncology setting preferred. Experience independently using at least 1 or more flow cytometry software programs (FlowJo, FCS Express, etc) is required. Knowledge of OMIQ analysis platform a plus. Experience in coding (R, Python, etc), Data Science or willingness to learn in support of role and tool building. Proficiency with Microsoft Word, Excel, PowerPoint; experience with MS Project is helpful. Role may involve infrequent travel to meet with key vendors. 

 

  • • This is a contract position at Regeneron with Magnit Global being the Employer. 

  • • To do our best work we need different viewpoints. Therefore, we celebrate diversity and embrace inclusion. As an equal opportunity employer, we are dedicated to building a team that represents a variety of backgrounds, perspectives, and skills. We strive to ensure that we maintain a positive and enriching work environment for all. 

 

Apply

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Posted August 10, 2023

Scholarships/Fellowship
EMBL

Executive fellowships for careers in service-providing research infrastructures (ARISE MSCA fellowships)

 

Are you an innovative thinker, eager to develop novel/improve existing tools, methods and technologies for the life sciences? Are you driven by curiosity and impact? Do you wish to become an expert in service development, provision and research infrastructure management in academia or industry? If so, we would like to hear from you! Here is why:

 

The life sciences are increasingly relying on advanced technologies and services provided by the core facilities, synchrotrons, data services and other research infrastructures. This creates a greater need for trained experts who know how to develop and operate scientific services. To meet this need, the ARISE programme (Career Accelerator for Research Infrastructure Scientists) at EMBL, is the first Fellowship programme of its kind in Europe that trains engineers and scientists for the high-level careers in research infrastructures in academia or industry.

 

You are invited to apply for one of the 30+ three-year Fellowships to

  • work at EMBL on a method, tool or technology development of your choice which will have a potential to be provided as a service to external life science researchers

  • get trained in the operation and management of research infrastructures and service provision. 

 

For the ARISE programme, we encourage applications from individuals who can complement our teams – we believe that success is built on having teams whose backgrounds and personal experiences reflect the diversity of the populations that our science serves. We are particularly interested in the strengths and lived experiences of women, and all genders, different ethnic groups and cultures, and all demographics to help us avoid perpetuating biases and oversights at this transformational point in our people strategy.

ARISE receives funding from Horizon 2020 under the Marie Skłodowska-Curie action COFUND (grant agreement No 945405).

 

What you will be doing

As an ARISE Fellow, you will be developing/improving a method, technique or technology of your choice which is in the field of expertise of EMBL groups who are participating in ARISE, e.g.:

  1. Bioinformatics, computational modelling, software development, data management, data science, AI and machine learning.

  2. Imaging and image analysis, optical engineering, detector development, microscopy, X-ray optics, X-ray crystallography.

  3. (Bio)chemical engineering, chemistry or chemical biology, omics technologies.

  4. Automation, high-precision mechanics, microfluidics, robotics.

 

Your development should facilitate research in life science fields of genome, structural, developmental and planetary biology, cell and tissue biology, translational research, or drug design and have the potential to be integrated into the service catalogues of research infrastructures.

You will get trained for jobs in research infrastructures (core facilities, data services, synchrotrons etc.) and attend over 60 courses on how to provide and plan services, how to manage the operation of diverse infrastructure, manage staff and finances, handle innovation and collaboration with industry, do strategic planning, and understand science policy and funding system.    

 

You will also be able to network with a diverse group of professionals working at EMBL and in ARISE partner organisations

The fellowship duration is 36 months.

 

You have

 

  • At least four years of full-time equivalent research or development experience in the fields mentioned above (including first experience in technology development), after the university degree.

  • University degree in natural sciences or related STEM disciplines (Science, Technology, Engineering and Mathematics) at the level which theoretically entitles you to enrol into a PhD (PhD is not mandatory).

  • A high level of skills or expertise, gained either in academic or non-academic sectors, relevant to the research fields of our  groups and teams that are participating in the programme.

  • Strong research and innovation potential which can be evidenced through various formats. Here is a non-exhaustive list of examples; example of your work on (scientific) software, unique or problematic data sets, technical documentation or similar, scientific publications, contributions to patents, examples of management of technology development projects or detailed description of any other innovative research you have performed and your achievements or through any other ways to demonstrate experience relevant to technology development and scientific services.

  • Capacity to work independently and think creatively.

  • Fluency in English (written and oral).

  • Ability to work collaboratively, and communicate and work with a diverse group of individuals across the organisation.

  • Good time management and organisation skills.

 

You might also have

 

  • Experience relevant to improvement or development of methods, techniques or technology that can be used for service provision.

  • A PhD degree.

Why you should join us

EMBL is Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international laboratory with more than 1800 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome. One of our missions is to provide access to advanced technologies and engage in technology transfer activities.

EMBL is a curiosity-driven, community-oriented and international organisation. As an inclusive, equal opportunity employer, we believe that diversity enables us to collaborate more effectively and be innovative in our approaches. We are, therefore, committed to creating an inclusive and flexible culture - one where everyone can realise their full potential and make a positive contribution to our organisation. We operate by our values of: openness, inclusion, integrity, transparency, fairness.

At EMBL, as per our Equality, Diversity and Inclusion Strategy, we actively encourage applications from people who are currently underrepresented in science.

We value our collegial and family-friendly working environment, and offer excellent health insurance, pension contributions, flexible hybrid working arrangements, family allowances, diverse training opportunities and other social benefits.

Salaries and allowances offered to the ARISE fellows are competitive and a full overview of salaries at different EMBL sites for ARISE fellows can be found here

Our working language is English.

 

How to apply
 

You will need to select the group you wish to join and prepare a short project proposal outlining the work you would like to do in the group. We strongly encourage you to contact the groups before applying, to inform them about your interest and learn about their future plans.

For details on how to apply, please visit our ARISE website. The application with all required documents should be submitted using the online submission system.

  • We accept applications from 1 July - 30 September 2023.

  • Interviews of top candidates are planned for late November 2023.

  • Start of the fellowship: ideally by May 2024.

Please contact the ARISE project management team (arise@embl.org) if you have any questions or need any kind of advice.

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Posted July 21, 2023

Flow Cytometry Facility Manager
Zuckerman Institute, Columbia University 
New York City

 
Join the Flow Cytometry Platform at the Zuckerman Mind Brain Behavior Institute at Columbia University and you will have the opportunity to be part of the cutting-edge neuroscience research happening here.  This essential flow cytometry lab is hiring a manager to handle all aspects of running the facility. The new manager will have the opportunity to assume the Director position. 


The successful candidate will be responsible for operating and troubleshooting a Beckman Coulter MoFlo Astrios EQ cell sorter and a Sony Biotechnology MA900 cell sorter.  You will operate and maintain the Astrios sorter.  The MA900 is an end user operated instrument.  You will train new users to operate this instrument correctly, oversee their experiments and do periodic maintenance.  Through your interactions with flow facility users you will be exposed to ongoing research activities at Zuckerman Institute such as studies on sensory receptors and connectivity, causes and treatment of neurodegenerative and psychological diseases, nervous system development and the molecular biology that describes what is going on in the cells that we sort.


The new manager should be knowledgeable about flow cytometry tools, techniques, protocols and have some biological laboratory experience.  Staying well versed in cutting edge technology and reagents for flow cytometry is essential for guiding facility users.  You will help users with experimental design that insures reproducible, accurate data and deliver high quality cell sorter output for downstream assays. This position requires a knowledgeable communicator that can inform users of the best way to set gates and sort the cells they need, recommend reagents that will improve the definition of cell populations of interest as well as analyze data. 


Flow cytometers are packed with optics, electronics, plumbing and mechanical parts.  The successful candidate must be a clever troubleshooter and manage to keep the instruments functioning when things go wrong. You will occasionally have to think outside the box and be ready to implement emergency repairs to complete ongoing experiments.  For serious problems, the resources of Beckman and Sony will help with instrument difficulties.  These instruments are under service contracts.


Candidates with 2+ years of flow cytometry experience are preferred.  If you have the skills but not the experience your application will also be considered.  Salary is commensurate with experience.  Zuckerman Mind Brain Behavior Institute is located at the Jerome L. Greene Science Center located at the Manhattanville campus of Columbia University near the main campus of Columbia University in New York City.  In addition to working with premiere faculty and students you will have all that NYC has to offer just out of the front door.  This position will become available in September 2023.

 

Contact:     Ira Schieren
                     Sr. Science Officer, Director of Flow Cytometry
                     Zuckerman Mind Brain Behavior Institute
                     Columbia University
                     is104@columbia.edu  
 

 

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Posted Feb 23, 2023

 

Principal Scientist - Oncology and Cell Therapy Flow Cytometry

Takeda

Boston, MA

Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

Job Description

The Flow Cytometry team within Clinical Biomarker Sciences and Operations (CBSO) department in the Precision & Translational Medicine (PTM) function at Takeda Oncology is seeking a highly motivated scientist to join our translational flow cytometry efforts for bringing novel medicines to cancer patients worldwide. This team is accountable as a subject-matter experts to ensure high-quality data generation of flow cytometry-based biomarker assays in all phases of clinical development in oncology/cell therapy at Takeda. The selected candidate will be responsible for building in-house capability as well as overseeing CROs for flow cytometry assay development, fit-for-purpose validation, and clinical sample analysis. The selected candidate must have strong background in multi-parameter flow cytometry, immunology, and translational sciences, for data quality assurance generated internally and externally as well as providing technical insights to translational and operational teams at Takeda.

Position Accountabilities

  • Conduct and oversee all aspects of conventional and spectral flow cytometry assay method development, validation, tech transfer, sample analysis and troubleshooting in clinical trials across Takeda oncology portfolio.

  • Oversee and interact with CROs to ensure qualities and timelines of outsourced flow cytometry assays.

  • Build in-house flow cytometry capability and perform experimental works to general high-quality data.

  • Communicate with project teams to understand scientific needs as well as update technical progress and data interpretation.

  • Able and willing to train other team members as required.

  • Help explore and test novel flow cytometry technologies and data analysis platforms.

Education, Experience, Knowledge And Skills

  • PhD in biochemistry, biology, medical technology, immunology, oncology, or similar.

  • 5+ years of post-PhD work experience in immunology, oncology, or a related field.

  • 2+ year work experience in pharmaceutical or biotechnology companies.

  • Immunological knowledge covering phenotyping of multiple subpopulations of cells.

  • Laboratory experience and understanding of high-dimensional flow cytometry biomarker assay development, fit-for-purpose validation, and clinical sample implementation.

  • Theoretical and practical understanding of flow cytometry with experience to design and execute 15+ color flow cytometry panels.

  • Considerable experience in the use of flow cytometry analysis software.

  • Expertise working with a variety of sample types including whole blood, PBMC, cell lines and single-cell suspension from tissue samples.

  • Deep knowledge of clinical trials and understanding of the role of biomarkers in clinical studies.

  • Excellent written, organizational, and interpersonal communications skills to update internal team members and stakeholders as well as interfacing with external vendors.

  • Strong attention to details, timelines, and quality.

  • Works successfully under pressure with tight timelines.

  • Proven critical reasoning skills including the identification and resolution of complex problems.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

What Takeda Can Offer You

  • 401(k) with company match and Annual Retirement Contribution Plan

  • Tuition reimbursement Company match of charitable contributions

  • Health & Wellness programs including onsite flu shots and health screenings

  • Generous time off for vacation and the option to purchase additional vacation days

  • Community Outreach Programs

Base Salary Range 143,500.00 to 205,000.00. Employees may also be eligible for Short Term and Long-Term Incentive benefits. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.

The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

Empowering Our People to Shine

Discover more at takedajobs.com

No Phone Calls or Recruiters Please.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Apply here.

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